onopordopicrin

structure given in first source; isolated from Centaurea sonchifolia; RN given is for (3aR-(3aR*,4S*,6E,10Z,11aR*))-isomer

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Colitis 03/07/2013 - "In the present study, we investigated the effects of the lactone sesquiterpene onopordopicrin enriched fraction (ONP fraction) from Arctium lappa in an experimental colitis model induced by 2,4,6 trinitrobenzene sulfonic acid and performed experiments to elucidate the underlying action mechanisms involved in that effect. "
2.	Neoplasms (Cancer) 12/01/2021 - "Onopordopicrin from the new genus Shangwua as a novel thioredoxin reductase inhibitor to induce oxidative stress-mediated tumor cell apoptosis."
3.	Muscular Diseases (Myopathy) 03/02/2021 - "Therefore, our results suggest that onopordopicrin may be a potential therapeutic molecule to fight against oxidative stress in pathological specific muscle disorders."

1.	Sulfonic Acids
2.	Sesquiterpenes
3.	Lactones
4.	Thioredoxin-Disulfide Reductase