with EC 2.4.1.148 this is called beta6-GlcNAc-transferase B; a key enzyme determining the structure of O-linked glycosylation; Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R; RefSeq NM_001490 (human); NM_010265 (mouse); NM_022276 (rat)
Also Known As:
C2GNT protein, human; C2GlcNAcT-I; C2TF; Core2GnT protein, human; GCNT1 protein, human; Gal3-GalNAc-mucin-6-GlcNAc transferase; Gcnt1 protein, mouse; Gcnt1 protein, rat; UDP-GlcNAc-Gal1-3GalNAc-R-(GlcNAc to GalNAc)-beta1-6GlcNAc transferase; beta-1,6-N-acetylglucosaminyltransferase, human; core 2 GlcNAc transferase; core 2 beta6-GlcNAc-transferase; core 2 beta6-Gn-T protein, human; core 2-N-acetylglucosaminyltransferase; glucosaminyl (N-acetyl) transferase 1, core 2, human; glucosaminyl (N-acetyl) transferase 1, core 2, mouse; glucosaminyl (N-acetyl) transferase 1, core 2, rat