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mecambridine
structure given in first source
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinolizines: 1
mecambridine: 1
Experts
1.
Li, Zhiping
: 1 article (01/2018)
2.
Lin, Na
: 1 article (01/2018)
3.
Wang, Deli
: 1 article (01/2018)
4.
Wang, Huiqi
: 1 article (01/2018)
5.
Wu, Yiyan
: 1 article (01/2018)
6.
Zheng, Kewen
: 1 article (01/2018)
Related Diseases
1.
Neoplasms (Cancer)
01/01/2018 - "
In conclusion, the present study suggests that mecambridine exhibits substantial anticancer activity against OSCC HSC-3 cells by induction of autophagy and modulates the expression of the mTOR/PI3K/Akt signaling cascade which is considered a potential target pathway for anti-cancer agents.
"
2.
Squamous Cell Carcinoma of Head and Neck
01/01/2018 - "
An MTT assay was used to evaluate cytotoxic effects of mecambridine on HSC-3 oral squamous cell carcinoma cells.
"
01/01/2018 - "
Mecambridine induces potent cytotoxic effects, autophagic cell death and modulation of the mTOR/PI3K/Akt signaling pathway in HSC-3 oral squamous cell carcinoma cells.
"
01/01/2018 - "
The present study aimed to evaluate the anticancer activity of a natural alkaloid, mecambridine, against human oral squamous cell carcinoma (OSCC).
"
Related Drugs and Biologics
1.
Alkaloids