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N-phenyl-N'-3-hydroxyphenylthiourea
Also Known As:
PTU 23; PTU-23
Networked:
4
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Urea: 15015
Thiourea: 362
Phenylthiourea: 102
N-phenyl-N'-3-hydroxyphenylthiourea: 4
Sulfur Compounds: 278
Thiourea: 362
Phenylthiourea: 102
N-phenyl-N'-3-hydroxyphenylthiourea: 4
Related Diseases
1.
Carcinoma (Carcinomatosis)
05/01/1983 - "
PTU-23, an effective in vivo wide-range enterovirus inhibitor, suppresses the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells at concentrations of 20-50 micrograms/ml, not affecting the cellular synthetic processes.
"
05/01/1983 - "
PTU-23, a selective inhibitor of the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells, counteracts the virus-induced shut-off of the host-cell protein synthesis reducing it from 32% to 19%.
"
2.
Ascites
05/01/1983 - "
PTU-23, an effective in vivo wide-range enterovirus inhibitor, suppresses the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells at concentrations of 20-50 micrograms/ml, not affecting the cellular synthetic processes.
"
05/01/1983 - "
PTU-23, a selective inhibitor of the reproduction of encephalomyocarditis (EMC) virus in Krebs-II ascites carcinoma cells, counteracts the virus-induced shut-off of the host-cell protein synthesis reducing it from 32% to 19%.
"
3.
Infections
01/01/1974 - "
Under the action of N-phenyl-N'-3-hydroxyphenylthiourea (no. 23) and N-phenyl-N'-4-carboxy-5-hydroxyphenylthiourea (no. 20) a two- to threefold reduction in mortality was observed, as well as an appreciable delay in the course of the disease (mean effective dose, lengthening by 2 to 6 days) after infection with Coxsackie viruses B1, B3, and A7.
"
4.
Body Weight (Weight, Body)
01/01/1986 - "
PTU-23 was administered subcutaneously in doses of 200, 400 and 800 mg/kg body weight during 6 consecutive days.
"
Related Drugs and Biologics
1.
Proteins (Proteins, Gene)