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bilitranslocase

plasma membrane protein involved in hepatic bilibubin & organic anion uptake in rats

Also Known As:

Translocase, bilirubin

Networked: 8 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Passamonti, Sabina: 3 articles (06/2013 - 01/2010)
2.	Brandoni, Anabel: 2 articles (11/2012 - 01/2010)
3.	Bonin, Serena: 1 article (06/2013)
4.	De Leo, Luigina: 1 article (06/2013)
5.	Montanic, Sendi: 1 article (06/2013)
6.	Rajcevic, Uros: 1 article (06/2013)
7.	Serbec, Vladka Curin: 1 article (06/2013)
8.	Terdoslavich, Michela: 1 article (06/2013)
9.	Bulacio, Romina Paula: 1 article (11/2012)
10.	Hazelhoff, María Herminia: 1 article (11/2012)

Related Diseases

1.	Kidney Neoplasms (Kidney Cancer) 06/01/2013 - "On the basis of previous results, specific IgM monoclonal antibodies were produced in BALB/c mice, in order to further improve and extend the immunological approach to the study of bilitranslocase in renal cancer cells as well as to develop its potential diagnostics use. "
2.	Gilbert Disease 06/01/1985 - "4. Since RSV competes with BSP for binding to bilitranslocase in vitro, the data are interpreted as suggesting that reduced bilitranslocase function might underlie the delayed RSV plasma clearance and the exacerbated unconjugated hyperbilirubinaemia present in Gilbert's syndrome." 01/01/1987 - "Because bilirubin and FFA partly share a common, bilitranslocase-mediated, hepatic uptake mechanism, data reported support the hypothesis that a bilitranslocase function may be one of the metabolic defects in Gilbert's syndrome." 06/01/1985 - "The implication of bilitranslocase function in the impaired rifamycin SV metabolism in Gilbert's syndrome." 11/01/1988 - "Nicotinic acid (NA) administration in Gilbert's syndrome (GS) patients promotes an increment of bilirubin and of total iron serum levels, dependent on a defective hepatic bilitranslocase function and on a haemolytic effect of NA. "
3.	Ischemia 05/01/2012 - "Cyanidin 3-glucoside was transported via bilitranslocase into endothelial cells, where it acted as a powerful intracellular antioxidant and a cardioprotective agent in the reperfusion phase after ischemia. "
4.	Hyperbilirubinemia 06/25/1999 - "The hypothesis that the uneven distribution of bilirubin in the organism, which occurs in hyperbilirubinemia, could reflect an uneven distribution of bilirubin-binding proteins was tested by searching for peptides containing the bilirubin-binding motif identified in bilitranslocase (Battiston et al., 1998). "
5.	Cholestasis 01/01/2010 - "The higher renal expression and function of bilitranslocase in renal basolateral membranes from rats with obstructive cholestasis might also contribute to the dramatic increase in BSP renal excretion observed in this experimental model. "

Related Drugs and Biologics

1.	Immunoglobulin M (IgM)
2.	Monoclonal Antibodies
3.	Bilirubin
4.	Peptides (Polypeptides)
5.	Carrier Proteins (Binding Protein)
6.	Organic Anion Transporters
7.	Biomarkers (Surrogate Marker)
8.	Sulfobromophthalein (Sulfobromophthalein Sodium)
9.	Sodium
10.	Niacin (Nicotinic Acid)