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2,2-dimethylthiazolidine (DMTD)

RN given refers to parent cpd; structure given in first source

Also Known As:

DMTD; 2,2-dimethylthiazolidine hydrochloride

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Thiazoles: 392
    - 2,2-dimethylthiazolidine: 4
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - 2,2-dimethylthiazolidine: 4

Experts

1.	Beale, Corinna N: 1 article (04/2022)
2.	Chen, Howard H: 1 article (04/2022)
3.	Gavini, Madhavi P: 1 article (04/2022)
4.	Ling, Lauren A: 1 article (04/2022)
5.	Martin, Gregory L: 1 article (04/2022)
6.	Mehm, Alexander: 1 article (04/2022)
7.	Mooney, Brian P: 1 article (04/2022)
8.	Pulakat, Lakshmi: 1 article (04/2022)
9.	Sun, Hongmin: 1 article (04/2022)
10.	Tang, Yinian: 1 article (04/2022)

Related Diseases

1.	Infections 04/30/2022 - "Thus, topical DMTD delivery of these antibiotics is a safe treatment for the difficult-to-treat deep skin tissue infections by MDR bacteria." 04/30/2022 - "coli infection was similar when treated with topical DMTD- or systemic IP (intraperitoneal)-delivered CMS; (2) DMTD-delivered micromist did not spread the infection deeper; (3) topical DMTD delivery and IP delivery resulted in similar levels of vancomycin in the skin after a 2 h washout period; and (4) IP-delivered vancomycin was about 1000-fold higher in kidney and plasma than DMTD-delivered vancomycin indicating systemic toxicity. " 04/30/2022 - "To overcome this difficulty, we tested if high molecular weight antibiotics delivered by Droplette micromist technology device (DMTD), a transdermal delivery device that generates a micromist capable of packaging large molecules, could attenuate deep skin tissue infections. " 04/30/2022 - "Transdermal Delivery of High Molecular Weight Antibiotics to Deep Tissue Infections via Droplette Micromist Technology Device (DMTD)."
2.	Hyperglycemia 11/01/2017 - "In this study, we synthesized an oxolane derivative 1-(2,2-dimethyltetrahydrofuro[2,3][1,3]dioxol-5-yl)ethane-1,2-diol (DMTD), and demonstrated its efficacy to mitigate hyperglycemia-induced ROS generation and subsequent eryptosis. "
3.	Critical Illness (Critically Ill) 10/25/2019 - "This description of the pharmacokinetics of DMTD, DG1, and DG2 in ICU patients is novel and suggests that pathophysiological changes in critically ill patients may have potential to decrease the glucuronidation of DMTD."
4.	Neoplasms (Cancer) 01/01/2020 - "Here, we systematically identified DMTD by integrative analysis of transcriptome, methylome and regulatome across 22 human cancer types. " 01/01/2020 - "However, the global landscape of DNA methylation-mediated transcriptional dysregulation (DMTD) across cancers has not been portrayed. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Ethane
3.	Vancomycin