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substance P degrading enzyme
neutral metallo-endopeptidase from human brain
Also Known As:
SPD enzyme; substance P endopeptidase
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Hydrolases: 2166
Peptide Hydrolases: 23957
Metalloproteases: 8276
Metalloendopeptidases: 70
substance P degrading enzyme: 4
Endopeptidases: 633
Metalloendopeptidases: 70
substance P degrading enzyme: 4
Related Diseases
1.
Low Back Pain (Lumbago)
11/01/1990 - "
The activity levels of a dynorphin converting enzyme (DCE), a substance P endopeptidase (SPE) and a substance P alpha-amidating enzyme (SP-GLYE) were measured in the cerebrospinal fluid (CSF) of 90 patients with chronic low back pain, sciatica and neurological signs of rhizopathy.
"
2.
Hip Osteoarthritis (Coxarthrosis)
04/01/1996 - "
We measured activities of dynorphin-converting enzyme (DCE), substance P endopeptidase (SPE) and angiotensin-converting enzyme (ACE) in cerebrospinal fluid (CSF) in 13 patients with rhizopathic pain from an herniated lumbar disc, in 9 patients with pain from coxarthrosis and in 11 control patients without pain.
"
3.
Spinal Cord Injuries (Spinal Cord Injury)
01/01/1997 - "
The influence of the new antioxidant compound H-290/51 was examined on the substance P endopeptidase (SPE) activity in a rat model of spinal cord injury.
"
4.
Sciatica (Sciatic Neuralgia)
11/01/1990 - "
The activity levels of a dynorphin converting enzyme (DCE), a substance P endopeptidase (SPE) and a substance P alpha-amidating enzyme (SP-GLYE) were measured in the cerebrospinal fluid (CSF) of 90 patients with chronic low back pain, sciatica and neurological signs of rhizopathy.
"
5.
Pain (Aches)
04/01/1996 - "
We measured activities of dynorphin-converting enzyme (DCE), substance P endopeptidase (SPE) and angiotensin-converting enzyme (ACE) in cerebrospinal fluid (CSF) in 13 patients with rhizopathic pain from an herniated lumbar disc, in 9 patients with pain from coxarthrosis and in 11 control patients without pain.
"
Related Drugs and Biologics
1.
dynorphin converting enzyme
2.
Substance P
3.
Enzymes
4.
Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)
5.
Dynorphins (Dynorphin)
6.
Collagen
7.
Antioxidants
8.
H290-51
9.
dynorphin A-converting enzyme