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oxoline
nasal ointment; contains 0.25% tetraoxotetrahydronaphthalene dihydrate; RN given refers to parent cpd; structure in Negwer, 5th ed, #1164
Also Known As:
oksolin; oxoline dihydrate; oxoline, 14C-labeled cpd; tetraoxotetrahydronaphthalene dihydrate; 1,2,3,4-naphthalenetetrone
Networked:
8
relevant articles (
1
outcomes,
2
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Tetrahydronaphthalenes: 1
oxoline: 8
Polycyclic Compounds: 6
Polycyclic Aromatic Hydrocarbons: 2020
Naphthalenes: 18
Tetrahydronaphthalenes: 1
oxoline: 8
Experts
1.
Czeizel, Andrew E
: 1 article (03/2006)
2.
Dudás, István
: 1 article (03/2006)
3.
Puhó, Erzsébet
: 1 article (03/2006)
Related Diseases
1.
Skin Diseases (Skin Disease)
12/01/1974 - "
[Therapeutic efficacy of oxoline and adimal in viral and presumedly viral dermatoses].
"
01/01/1972 - "
[Use of oxoline ointment for the treatment of some viral dermatoses].
"
2.
Human Influenza (Influenza)
09/01/1970 - "
[Results of clinical studies on the prophylactic and therapeutic effectiveness of oxoline on artificially induced influenza A2 infection in volunteers].
"
11/01/1973 - "
[Experience in the use of oxoline ointment in the prevention of influenza].
"
01/01/1970 - "
[Evaluation of the preventive effectiveness in influenza of the new native antiviral chemical agent oxoline in the 1969 epidemics].
"
3.
Urinary Tract Infections (Urinary Tract Infection)
03/01/2006 - "
The objective of the study was to check the effect of oxoline acid, a bactericidal drug for the treatment of urinary tract infection during pregnancy, on congenital abnormalities of informative offspring and fetal development.
"
4.
Infections
09/01/1970 - "
[Results of clinical studies on the prophylactic and therapeutic effectiveness of oxoline on artificially induced influenza A2 infection in volunteers].
"
5.
Congenital Abnormalities (Deformity)
03/01/2006 - "
The comparison of observed and expected number of different congenital abnormalities did not show the teratogenic potential of oxoline acid.
"
03/01/2006 - "
Of 38,151 newborn infants without any congenital abnormalities (control group), 13 (0.03%) had mothers who were treated with oxoline acid, while of 22,843 cases with congenital abnormalities, five (0.02%) had mothers who were treated with oxoline acid during pregnancy (POR with 95% CI: 0.6, 0.2-1.8).
"
03/01/2006 - "
Observed and expected numbers of congenital abnormalities were compared in the newborn infants and fetus of case mothers with oxoline acid treatment.
"
03/01/2006 - "
The teratogenic and fetotoxic potential of oxoline acid was evaluated in the population-based large data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996.
"
03/01/2006 - "
The objective of the study was to check the effect of oxoline acid, a bactericidal drug for the treatment of urinary tract infection during pregnancy, on congenital abnormalities of informative offspring and fetal development.
"
Related Drugs and Biologics
1.
adimal
2.
Acids
3.
Ointments (Pastes)
4.
Antiviral Agents (Antivirals)