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parishin

Also Known As:

parishin A

Networked: 8 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Glucosides: 639
    - parishin: 8

Experts

1.	Xiang, Lan: 2 articles (07/2022 - 01/2022)
2.	Zhang, Qin: 2 articles (07/2022 - 01/2022)
3.	Chen, Si-Min: 1 article (07/2022)
4.	Gong, Cai-Xia: 1 article (07/2022)
5.	Irge, Dejene Disasa: 1 article (07/2022)
6.	Li, Han-Yu: 1 article (07/2022)
7.	Li, Jin-You: 1 article (07/2022)
8.	Li, Shu-Min: 1 article (07/2022)
9.	Ma, Cheng: 1 article (07/2022)
10.	Yang, Yun-Mei: 1 article (07/2022)

Related Diseases

1.	Fibrosis (Cirrhosis) 01/01/2022 - "The results showed that parishin treatment ameliorates aging-induced cardiopulmonary fibrosis and increase in serum p16 Ink4a , GDF15, and IL-6 levels. "
2.	Tendinopathy (Tendonitis) 03/10/2023 - "Parishin A-loaded mesoporous silica nanoparticles modulate macrophage polarization to attenuate tendinopathy." 03/10/2023 - "In this study, we find that a small molecule compound Parishin-A (PA) isolated from Gastrodia elata could promote anti-inflammatory M2 macrophage polarization by inhibiting gene transcription and protein phosphorylation of signal transducers and activators of transcription 1. Local injection or sustained delivery of PA by mesoporous silica nanoparticles (MSNs) could almost recover the native tendon's dense parallel-aligned collagen matrix in collagenase-induced tendinopathy by modulating macrophage-mediated immune microenvironment and preventing heterotopic ossification. "
3.	Heterotopic Ossification (Ectopic Ossification) 03/10/2023 - "In this study, we find that a small molecule compound Parishin-A (PA) isolated from Gastrodia elata could promote anti-inflammatory M2 macrophage polarization by inhibiting gene transcription and protein phosphorylation of signal transducers and activators of transcription 1. Local injection or sustained delivery of PA by mesoporous silica nanoparticles (MSNs) could almost recover the native tendon's dense parallel-aligned collagen matrix in collagenase-induced tendinopathy by modulating macrophage-mediated immune microenvironment and preventing heterotopic ossification. "
4.	Cognition Disorders 01/01/2016 - "In order to compare the pharmacological effects of gastrodin, parishin and parishin C on improving cognition deficits, we tested them in an animal model of cognition disorders induced by scopolamine and in a study of in vivo long-term potentiation (LTP) recordings. "
5.	Dysbiosis 01/01/2022 - "Furthermore, parishin treatment alleviated dysbiosis in gut microbiota, including altered microbial diversity and the aberrant abundance of opportunistic pathogenic bacteria such as Turicibacter and Erysipelatoclostridium. "

Related Drugs and Biologics

1.	Cyclin-Dependent Kinase Inhibitor p16
2.	Interleukin-6 (Interleukin 6)
3.	Proteins (Proteins, Gene)
4.	Collagenases (Collagenase)
5.	Silicon Dioxide (Silica)
6.	Scopolamine (Hyoscine)
7.	Collagen
8.	parishin C
9.	gastrodin
10.	Tight Junction Proteins