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ferulin C

sesquiterpene coumarin, isolated from the roots of Ferula ferulaeoides (Steud.)

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        ferulin C: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        ferulin C: 1
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - ferulin C: 1

Experts

1.	He, Zhendan: 1 article (01/2020)
2.	Huang, Jian: 1 article (01/2020)
3.	Pan, Dabo: 1 article (01/2020)
4.	Wang, Jinhui: 1 article (01/2020)
5.	Yao, Dahong: 1 article (01/2020)
6.	Zhang, Jin: 1 article (01/2020)
7.	Zhen, Yongqi: 1 article (01/2020)

Related Diseases

1.	Breast Neoplasms (Breast Cancer) 01/01/2020 - "This study aimed to elucidate the underlying molecular mechanisms of Ferulin C-induced breast cancer cells death in vitro and in vivo. " 01/01/2020 - "Summarily, our findings substantiated that Ferulin C was a potent, colchicine site binding microtubule-destabilizing agent with anti-proliferation and anti-metastasis activity via PAK1 and p21-mediated signaling in breast cancer cells." 01/01/2020 - "Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo." 01/01/2020 - "Ferulin C, a natural sesquiterpene coumarin, isolated from the roots of Ferula ferulaeoides (Steud.) Korov, displaying potent antiproliferatory activity against breast cancer cells. "
2.	Weight Loss (Weight Reduction) 01/01/2020 - "Additionally, Ferulin C displayed an acceptable antiproliferatory activity in an MCF-7 xenograft model without inducing obvious weight loss in the Ferulin C treated mice. "
3.	Neoplasms (Cancer) 01/01/2020 - "Ferulin C triggers potent PAK1 and p21-mediated anti-tumor effects in breast cancer by inhibiting Tubulin polymerization in vitro and in vivo."
4.	Neoplasm Metastasis (Metastasis) 01/01/2020 - "Intriguingly, Ferulin C treatment induced autophagy by ULK1 signaling to synergize with the inhibition of proliferation and metastasis. " 01/01/2020 - "Furthermore, Ferulin C stimulated significant cell cycle arrest in the G1/S period via p21Cip1/Waf1 - CDK2 signaling, induced classic cell apoptosis, impaired metastasis via down-regulating Ras-Raf-ERK and AKT-mTOR signaling. " 01/01/2020 - "Summarily, our findings substantiated that Ferulin C was a potent, colchicine site binding microtubule-destabilizing agent with anti-proliferation and anti-metastasis activity via PAK1 and p21-mediated signaling in breast cancer cells."

Related Drugs and Biologics

1.	Tubulin
2.	Sesquiterpenes
3.	Colchicine
4.	coumarin