UiO-66

10/20/2021 - "Serial positron emission tomography (PET) imaging demonstrated that the preferential accumulation of 89Zr-UiO-66-PEG-F3 in MDA-MB-231 tumors, and their liver clearance was faster than PEGylated UiO-66 using noncovalent methods. "
02/14/2018 - "DCA-loaded, FA-modified UiO-66 selectively kills cancer cells without harming healthy ones or provoking immune system response in vitro, suggesting a significant targeting effect and great potential in anticancer drug delivery. "
11/18/2020 - "Here, we analyze doxorubicin delivery to cancer cells by MIL-101(Cr) and UiO-66 in real time. "
08/21/2017 - "The Pc-containing UiO-66 nanomaterials exhibit high photodynamic activity, and the Erlotinib-containing UiO-66 nanomaterials show obvious dark cytotoxicity and high selective affinity to cancer cells. "
04/01/2023 - "Synthesis of Gingerol-loaded Uio-66 nanoparticles and its anti-cancer effect against gastric cancer cell line (AGS)."

01/27/2021 - "In this study, a novel type of UiO-66 with a smaller particle size, namely, UiO-66S, was used as a decontaminant for the blister agent simulant, 2-chloroethyl ethyl sulfide (2-CEES). "

06/27/2023 - "The resulted UiO-66 membranes with fast water selective transport channels exhibited unprecedentedly high solvent dehydration performance with a permeation flux of ∼6100 g m-2 h-1 and a separation factor of ∼7500, showing great potential for intensification of esterification reaction."
08/03/2020 - "Characterization reveals that UiO-66-PO3 H2 retains stability similar to UiO-66, and exhibits weak Brønsted acidity, as demonstrated by titrations, alcohol dehydration, and dehydra-decyclization of 2-methyltetrahydrofuran (2-MTHF). "
03/14/2018 - "UiO-66 is a showcase example of an extremely stable metal-organic framework, which maintains its structural integrity during activation processes such as linker exchange and dehydration. "
07/08/2021 - "We now show that the MOF hcp UiO-66, which incorporates dimeric Zr6O8 nodes bridged by μ2-OH groups, is an excellent platform for identifying and controlling adjacent sites consisting of OH groups and Zr4+ sites, which catalyze tert-butyl alcohol dehydration much more rapidly than isolated single sites."
07/08/2021 - "Pair Sites on Nodes of Metal-Organic Framework hcp UiO-66 Catalyze tert-Butyl Alcohol Dehydration."

07/05/2022 - "Afterward, in vitro cytotoxicity and hemolysis assays were performed to investigate UiO-66 biocompatibility. "
11/30/2023 - "The hemolysis test, coagulation time test, and cytotoxicity test confirmed that the bilirubin adsorbents based on UiO-66 and UiO-66-NH2 have good blood compatibility and biocompatibility. "

01/01/2021 - "Oxaliplatin is being used in different malignancies and several side effects are reported for patients taking Oxaliplatin, including peripheral neuropathy, nausea and vomiting, diarrhea, mouth sores, low blood counts, fatigue, loss of appetite, etc. Here we have developed a targeted anticancer drug delivery system based on folate-conjugated amine-functionalized UiO-66 for the delivery of oxaliplatin (OX). "