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N-(4methyl-phenyl)-4-methylphthalimide

Also Known As:

MPMPH-1

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Phthalic Acids: 1
      - Phthalimides: 12
        N-(4methyl-phenyl)-4-methylphthalimide: 2
- Imides: 79
  - Phthalimides: 12
    - N-(4methyl-phenyl)-4-methylphthalimide: 2
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - Phthalimides: 12
        N-(4methyl-phenyl)-4-methylphthalimide: 2

Experts

1.	Corrêa, Rogério: 2 articles (01/2019 - 12/2017)
2.	Braga, Rodolpho C: 1 article (01/2019)
3.	Broering, Milena F: 1 article (01/2019)
4.	Dos Santos, Carlos E M: 1 article (01/2019)
5.	Filho, Valdir C: 1 article (01/2019)
6.	Nunes, Roberta: 1 article (01/2019)
7.	Pastor, Maria V D: 1 article (01/2019)
8.	Quintão, Nara L M: 1 article (01/2019)
9.	Santin, José R: 1 article (01/2019)
10.	Stiz, Dorimar S: 1 article (01/2019)

Related Diseases

1.	Hypersensitivity (Allergy) 01/01/2019 - "Additionally, the repeated treatment of mice with MPMPH-1 (10 mg/kg, i.p.), once a day for up to 36 days, significantly reduces the hypersensitivity in animals with breast cancer bone metastasis. " 12/01/2017 - "Anti-hypersensitivity effects of the phthalimide derivative N-(4methyl-phenyl)-4-methylphthalimide in different pain models in mice." 12/01/2017 - "MPMPH-1 was also effective in reducing the hypersensitivity induced by IL-1β, bradykinin, prostaglandin E2 or epinephrine, chemical mediators that have, among others, AC as pivotal protein in their signalling cascade to induce mechanical-pain behaviour. "
2.	Pain (Aches) 12/01/2017 - "Anti-hypersensitivity effects of the phthalimide derivative N-(4methyl-phenyl)-4-methylphthalimide in different pain models in mice." 12/01/2017 - "MPMPH-1 was also effective in reducing the hypersensitivity induced by IL-1β, bradykinin, prostaglandin E2 or epinephrine, chemical mediators that have, among others, AC as pivotal protein in their signalling cascade to induce mechanical-pain behaviour. "
3.	Neoplasm Metastasis (Metastasis) 01/01/2019 - "Considering the literature data, the present study evaluated the effects of MPMPH-1 on breast cancer bone metastasis and correlated painful symptom, and provided additional toxicological information about the compound and its possible metabolites. " 01/01/2019 - "MPMPH-1 treatments in the breast cancer bone metastasis model were able to prevent the osteoclastic resorption of bone matrix. " 01/01/2019 - "Additionally, the repeated treatment of mice with MPMPH-1 (10 mg/kg, i.p.), once a day for up to 36 days, significantly reduces the hypersensitivity in animals with breast cancer bone metastasis. "
4.	Breast Neoplasms (Breast Cancer) 01/01/2019 - "Considering the literature data, the present study evaluated the effects of MPMPH-1 on breast cancer bone metastasis and correlated painful symptom, and provided additional toxicological information about the compound and its possible metabolites. " 01/01/2019 - "MPMPH-1 treatments in the breast cancer bone metastasis model were able to prevent the osteoclastic resorption of bone matrix. " 01/01/2019 - "Additionally, the repeated treatment of mice with MPMPH-1 (10 mg/kg, i.p.), once a day for up to 36 days, significantly reduces the hypersensitivity in animals with breast cancer bone metastasis. "
5.	Neoplasms (Cancer) 01/01/2019 - "Together, the data herein obtained show that MPMPH-1 is relatively safe, and significantly control the cancer growth, allied to the reduction in bone reabsorption and stimulation of bone and cartilage regeneration. "

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Proteins (Proteins, Gene)
3.	Epinephrine (Adrenaline)
4.	Bradykinin
5.	phthalimide