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benapenem

a carbapenem

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amides: 2428
  - Lactams: 2198
    - beta-Lactams: 2386
      - Carbapenems: 4837
        benapenem: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - beta-Lactams: 2386
      - Carbapenems: 4837
        benapenem: 1

Experts

1.	Ji, Xi-Wei: 1 article (01/2020)
2.	Kang, Zi-Sheng: 1 article (01/2020)
3.	Kuan, Isabelle Hui-San: 1 article (01/2020)
4.	Li, Yun: 1 article (01/2020)
5.	Lv, Yuan: 1 article (01/2020)
6.	Xue, Feng: 1 article (01/2020)
7.	Yang, Xi-Ping: 1 article (01/2020)
8.	Zhong, Wei: 1 article (01/2020)
9.	Zhu, Xiao: 1 article (01/2020)

Related Diseases

1.	Bacterial Infections (Bacterial Infection) 01/01/2020 - "The objective of this study was to determine the pharmacokinetic (PK)/pharmacodynamic (PD) cutoff values and evaluate the optimal administration regimens of benapenem for the treatment of bacterial infections via PK/PD modeling and simulation. "
2.	Infections 01/01/2020 - "Monte Carlo simulations were employed to determine the cutoff values and the appropriate benapenem dosing regimens for the treatment of infections caused by clinical isolates of Enterobacteriaceae Two 2-compartment models were developed to describe the PK profiles of benapenem in humans and mice. "
3.	Enterobacteriaceae Infections 01/01/2020 - "The established model provides a better understanding of the pharmacological properties of benapenem for the treatment of Enterobacteriaceae infections. "
4.	Body Weight (Weight, Body) 01/01/2020 - "Infected mice received an intravenous (i.v.) injection of benapenem or ertapenem of 14.6, 58.4, or 233.6 mg/kg of body weight, and the PK/PD profiles were evaluated. "

Related Drugs and Biologics

1.	Ertapenem (Invanz)