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lanceolatin B

interacts with CYP1A1

Also Known As:

2-phenyl-4H-furo(2,3-h)chromen-4-one; 4H-furo(2,3-h)-1-benzopyran-4-one, 2-phenyl-

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - lanceolatin B: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - lanceolatin B: 2

Experts

1.	Bharate, Sandip B: 1 article (12/2018)
2.	Chaudhuri, Bhabatosh: 1 article (12/2018)
3.	Gatchie, Linda: 1 article (12/2018)
4.	Sharma, Rajni: 1 article (12/2018)
5.	Sonawane, Vinay R: 1 article (12/2018)
6.	Williams, Ibidapo S: 1 article (12/2018)

Related Diseases

1.	Neoplasms (Cancer) 12/15/2018 - "The results strongly indicate the potential of methanolic seed-extract and pongapin/lanceolatin B for further development as cancer chemopreventive agents."
2.	Hepatocellular Carcinoma (Hepatoma) 09/01/1997 - "An isoflavone, 7,4'-dihydroxy-3',5'-dimethoxyisoflavone (1), and a chalcone, (+)-tephropurpurin (2), both novel compounds, as well as six constituents of known structure, (+)-purpurin (3), pongamol (4), lanceolatin B (5), (-)-maackiain (6), (-)-3-hydroxy-4-methoxy-8,9-methylene-dioxypterocarpan (7), and (-)-medicarpin (8), were obtained as active compounds from Tephrosia purpurea, using a bioassay based on the induction of quinone reductase (QR) activity with cultured Hepa 1c1c7 mouse hepatoma cells. "
3.	Breast Neoplasms (Breast Cancer) 12/15/2018 - "Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells."

Related Drugs and Biologics

1.	NAD(P)H Dehydrogenase (Quinone) (Quinone Reductase)
2.	Isoflavones
3.	Chalcone (Benzalacetophenone)
4.	pongamol
5.	medicarpin
6.	inermin
7.	pongapin