HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

norbelladine

common metabolic intermediate

Also Known As:

4-(((2-(4-Hydroxyphenyl)ethyl)amino)methyl)-1,2-benzenediol

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Biogenic Amines: 992
    - Biogenic Monoamines: 29
      - Tyramine: 552
        norbelladine: 2

Experts

1.	Baba, T: 1 article (01/2001)
2.	Hamamichi, N: 1 article (01/2001)
3.	Hamashima, Y: 1 article (01/2001)
4.	Kodama, S: 1 article (01/2001)
5.	Nishide, K: 1 article (01/2001)
6.	Node, M: 1 article (01/2001)

Related Diseases

1.	Alzheimer Disease (Alzheimer's Disease) 01/01/2001 - "Old problems, new ideas! The biomimetic phenol coupling of norbelladine derivatives such as 1 (Bn = benzyl) to form galanthamine (2), a drug used in the treatment of Alzheimer's disease, has been greatly improved by the use of the hypervalent-iodine oxidation reagent phenyliodine(III) bis(trifluoroacetate) (PIFA). "
2.	Neoplasms (Cancer) 08/31/2022 - "To gain insight into their therapeutic potential, we synthesized a series of O-methylated norbelladine-type alkaloids and evaluated their cytotoxic effects on two types of cancer cell lines, their antiviral effects against the dengue virus (DENV) and the human immunodeficiency virus 1 (HIV-1), and their anti-Alzheimer’s disease (anti-cholinesterase and -prolyl oligopeptidase) properties. "
3.	Leukemia 08/31/2022 - "In monocytic leukemia cells, norcraugsodine was highly cytotoxic (CC50 = 27.0 μM), while norbelladine was the most cytotoxic to hepatocarcinoma cells (CC50 = 72.6 μM). "

Related Drugs and Biologics

1.	Phenol (Carbolic Acid)
2.	Iodine
3.	Indicators and Reagents (Reagents)
4.	Galantamine (Galanthamine)
5.	phenyliodine(III) bis(trifluoroacetate)
6.	Cholinesterase Inhibitors (Anticholinesterases)
7.	Antiviral Agents (Antivirals)
8.	Alkaloids
9.	Prolyl Oligopeptidases