HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

MH-79 compound

an alpha1-adrenoceptor agonist with vasorelaxant properties

Also Known As:

1-((2-chlor-6-methylphenoxy)propyl)-4-(2-methoxyphenyl)piperazine hydrochloride; MH-79

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - MH-79 compound: 2

Experts

1.	Filipek, Barbara: 2 articles (01/2019 - 01/2019)
2.	Kotańska, Magdalena: 2 articles (01/2019 - 01/2019)
3.	Kubacka, Monika: 2 articles (01/2019 - 01/2019)
4.	Marona, Henryk: 2 articles (01/2019 - 01/2019)
5.	Mogilski, Szczepan: 2 articles (01/2019 - 01/2019)
6.	Nowak, Barbara: 1 article (01/2019)
7.	Pociecha, Krzysztof: 1 article (01/2019)
8.	Szafarz, Małgorzata: 1 article (01/2019)
9.	Waszkielewicz, Anna M: 1 article (01/2019)
10.	Waszkielewicz, Anna Maria: 1 article (01/2019)

Related Diseases

1.	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/01/2019 - "We investigated if MH-76 and MH-79, non-quinazoline α1-adrenoceptor antagonists with an additional ability to stimulate NO/cGMP/K+ pathway, ameliorates metabolic syndrome in fructose-fed rats. "
2.	Hypertrophy 01/01/2019 - "This study showed that the administration of MH-79 and, to a lesser extent, MH-76 decreased elevated systolic blood pressure and heart rate, reduced heart and kidney hypertrophy, and reversed the histopathological alterations of the heart, kidney, and vessels in DOCA-salt hypertensive rats. "
3.	Hypertension (High Blood Pressure) 01/01/2019 - "We investigated the therapeutic effect of MH-76 and MH-79, which are non-quinazoline α1-adrenoceptor antagonists with an additional ability to stimulate the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP)/K + pathway, on deoxycorticosterone acetate (DOCA)-salt induced hypertension in rats. "
4.	Fibrosis (Cirrhosis) 01/01/2019 - "MH-79 reversed endothelial dysfunction, which reduced inflammatory cell infiltration, arteriosclerotic alterations in renal and coronary arteries, and tubulointerstitial fibrosis. "

Related Drugs and Biologics

1.	MH-76 compound
2.	Quinazolines
3.	Fructose
4.	Desoxycorticosterone Acetate (DOCA)
5.	Salts
6.	Therapeutic Uses
7.	Nitric Oxide (Nitrogen Monoxide)
8.	Guanosine Monophosphate (5' Guanylic Acid)
9.	Desoxycorticosterone (Deoxycorticosterone)
10.	Acetates (Acetic Acid Esters)