haprolid

macrolactone isolated from Byssovorax cruenta Har1; has cytotoxic properties

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

1.	Neoplasms (Cancer) 03/06/2020 - "The efficacy of haprolid was evaluated in human HCC cell lines (Huh-7, Hep3B and HepG2) and xenograft tumors (NMRI-Foxn1nu mice with injection of Hep3B cells). " 03/06/2020 - "Finally, in vivo nude mice experiments demonstrated significant inhibition of tumor growth upon haprolid treatment. " 03/06/2020 - "Haprolid Inhibits Tumor Growth of Hepatocellular Carcinoma through Rb/E2F and Akt/mTOR Inhibition." 03/06/2020 - "Haprolid has been reported as a potent selective cytotoxin against a panel of tumor cells in recent studies including HCC cells. "
2.	Hepatocellular Carcinoma (Hepatoma) 03/06/2020 - "Haprolid Inhibits Tumor Growth of Hepatocellular Carcinoma through Rb/E2F and Akt/mTOR Inhibition."

1.	Cytotoxins (Cytolysins)