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histamine H3R antagonist 2-18

has anti-convulsant effect in mice

Also Known As:

H3R antagonist 2-18

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - histamine H3R antagonist 2-18: 1

Experts

1.	Abdulrazzaq, Yousef M: 1 article (01/2018)
2.	Bastaki, Salim M: 1 article (01/2018)
3.	Kieć-Kononowicz, Katarzyna: 1 article (01/2018)
4.	Sadek, Bassem: 1 article (01/2018)
5.	Shafiullah, Mohamed: 1 article (01/2018)
6.	Więcek, Małgorzata: 1 article (01/2018)

Related Diseases

1.	Epilepsy (Aura) 01/01/2018 - "In conclusion, the novel H3R antagonist 2-18 proves to be a very safe compound and displays a low incidence of malformations, demonstrating that H3R antagonist 2-18 may have a potential future therapeutic value in epilepsy."
2.	Body Weight (Weight, Body) 01/01/2018 - "Moreover, the results show that acute systemic administration of single (7.5, 15, 30, or 60 mg/kg, i.p.) or multiple doses (15×3 mg/kg, i.p.) of H3R antagonist 2-18 on gestation day (GD) 8 or 13 did not affect the maternal body weight of mice when compared with the control group. "