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NISC-6

structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        NISC-6: 2
- Nitriles: 227
  - NISC-6: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - NISC-6: 2

Experts

1.	Amin, Shantu: 2 articles (01/2019 - 07/2017)
2.	Sharma, Arun K: 2 articles (01/2019 - 07/2017)
3.	Berrio, Carlos: 1 article (01/2019)
4.	Fernández-Rubio, Celia: 1 article (01/2019)
5.	Gamboa, Iñigo: 1 article (01/2019)
6.	Larrea, Esther: 1 article (01/2019)
7.	Nguewa, Paul A: 1 article (01/2019)
8.	Peña Guerrero, José: 1 article (01/2019)
9.	Plano, Daniel: 1 article (01/2019)
10.	Sesma Herrero, Eduardo: 1 article (01/2019)

Related Diseases

1.	Neoplasms (Cancer) 07/28/2017 - "Furthermore, NISC-6 effectively induced apoptosis in human melanoma cells, inhibited tumor growth by ∼69% in a melanoma mouse xenograft model, and showed excellent compliance with the Lipinski' rule of five, suggesting both its efficacy and drug-like behavior under physiological conditions."
2.	Melanoma (Melanoma, Malignant) 07/28/2017 - "Furthermore, NISC-6 effectively induced apoptosis in human melanoma cells, inhibited tumor growth by ∼69% in a melanoma mouse xenograft model, and showed excellent compliance with the Lipinski' rule of five, suggesting both its efficacy and drug-like behavior under physiological conditions." 07/28/2017 - "Design, synthesis, and identification of a novel napthalamide-isoselenocyanate compound NISC-6 as a dual Topoisomerase-IIα and Akt pathway inhibitor, and evaluation of its anti-melanoma activity."
3.	Leishmaniasis 01/01/2019 - "Altogether, our data suggest that the isoselenocyanate NISC-6 may be a promising candidate for new drug development against leishmaniasis."

Related Drugs and Biologics

1.	isoselenocyanate