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NOX-D21

a PEGylated mixed L-RNA/DNA Spiegelmer that is an antagonsit of complement C5a

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleotides: 15763
  - Polynucleotides: 218
    - Oligonucleotides: 5145
      - Nucleotide Aptamers: 598
        NOX-D21: 2

Experts

1.	Chan, Kam Wa: 1 article (01/2018)
2.	Chan, Loretta Y Y: 1 article (01/2018)
3.	Lai, Kar Neng: 1 article (01/2018)
4.	Leung, Joseph C K: 1 article (01/2018)
5.	Li, Rui Xi: 1 article (01/2018)
6.	Sacks, Steven H: 1 article (01/2018)
7.	Tang, Sydney C W: 1 article (01/2018)
8.	Wong, Dickson W L: 1 article (01/2018)
9.	Wu, Hao Jia: 1 article (01/2018)
10.	Yiu, Wai Han: 1 article (01/2018)

Related Diseases

1.	Fibrosis (Cirrhosis) 01/01/2018 - "Blockade of C5a signalling by NOX-D21 moderates altered lipid metabolism in diabetes and improved tubulointerstitial fibrosis by reduction of lipid accumulation and TGF-β-driven fibrosis in diabetic kidney."
2.	Inflammation (Inflammations) 05/01/2017 - "Low-Intensity Training and the C5a Complement Antagonist NOX-D21 Rescue the mdx Phenotype through Modulation of Inflammation."

Related Drugs and Biologics

1.	Lipids
2.	Complement C5a (Complement 5a)