liposome-encapsulated hemoglobin

02/01/2010 - "Liposome-encapsulated hemoglobin ameliorates ischemic stroke in nonhuman primates: an acute study."
10/01/2013 - "Liposome-encapsulated hemoglobin ameliorates ischemic stroke in nonhuman primates: longitudinal observation."
01/01/2010 - "We performed this study to elucidate whether a newly developed liposome-encapsulated hemoglobin, TRM-645 (TRM), can prevent cerebral dysfunction resulting from acute ischemic stroke when used as an oxygen carrier. "
02/01/2009 - "Liposome-encapsulated hemoglobin (LEH) with a low oxygen affinity (l-LEH, P(50) = 45 mm Hg) was found to be protective in the rodent and primate models of ischemic stroke. "
01/01/2010 - "Liposome-encapsulated hemoglobin TRM might have therapeutic potentials for protecting the brain from neurological complications associated with acute ischemic stroke, as a promising blood substitute for oxygen therapy."

08/01/2014 - "Efficacy of liposome-encapsulated hemoglobin in a rat model of cerebral ischemia."
01/01/2010 - "Liposome-encapsulated hemoglobin ameliorates impairment of fear memory and hippocampal dysfunction after cerebral ischemia in rats."
08/01/2014 - "Liposome-encapsulated hemoglobin with low O2 -affinity (l-LEH) was shown to be protective in focal brain ischemia and reperfusion (I/R) in rats and primates. "
08/01/2014 - "Effects of liposome-encapsulated hemoglobin on learning ability in tokai high-avoider rat after total brain ischemia and reperfusion."
10/01/2013 - "Liposome-encapsulated hemoglobin (LEH) is protective early after brain ischemia in rats and nonhuman primates, but it remains unclear whether the protection persists and confers any benefits beyond the acute phase of brain ischemia and reperfusion. "

01/01/1994 - "The purpose of this study was to evaluate the effects of liposome encapsulated hemoglobin named "Neo Red Cells (NRC)" on canine hemorrhagic shock model and its safety for the vital organs in a whole blood exchange model. "
01/01/1992 - "The purpose of this study is to evaluate the newly developed liposome-encapsulated hemoglobin, named Neo Red Cells (NRC), in the treatment of hemorrhagic shock. "
01/01/1998 - "We examined the effects of liposome-encapsulated hemoglobin, neo red cells (NRCs), on hemorrhagic shock in a canine model. "
01/01/1998 - "Effect of liposome-encapsulated hemoglobin, neo red cells, on hemorrhagic shock."
07/01/1997 - "Effect of liposome encapsulated hemoglobin "neo red cells" on severe hemorrhagic shock."

08/01/2012 - "The use of liposome-encapsulated hemoglobin (LHb), which is a cellular Hb, has been demonstrated to be beneficial in the treatment of hypohemoglobinemic shock. "
08/01/2012 - "Liposome-encapsulated hemoglobin attenuates cardiac dysfunction and sympathetic activity during hypohemoglobinemic shock."
09/01/2015 - "The brain metabolic activity after resuscitation with liposome-encapsulated hemoglobin in a rat model of hypovolemic shock."
01/01/2011 - "Intraosseous transfusion with liposome-encapsulated hemoglobin improves mouse survival after hypohemoglobinemic shock without scavenging nitric oxide."
06/01/1998 - "Effect of liposome-encapsulated hemoglobin on the development of endotoxin-induced shock in the rat."

08/01/2014 - "Liposome-encapsulated hemoglobin with high O2 -affinity (P50 O2  = 10 mm Hg, h-LEH) was reported to enhance tumor radiosensitivity. "
02/01/2012 - "Liposome-encapsulated hemoglobin ameliorates tumor hypoxia and enhances radiation therapy to suppress tumor growth in mice."
04/01/2017 - "Liposome-encapsulated hemoglobin (LEH) with high (h-LEH, P50 O2  = 10 mm Hg) or low O2 affinity (l-LEH, P50 O2  = 40 mm Hg) may improve O2 delivery to sensitize tumor tissues for radiotherapy. "
02/01/2012 - "We hypothesize that liposome-encapsulated hemoglobin with high O₂ affinity (P₅₀0₂ = 12 mm Hg, h-LEH) may increase O₂ delivery to hypoxic tumors and enhance radiation therapy synergistically to suppress tumor growth. "
04/01/2017 - "Liposome-Encapsulated Hemoglobin Improves Tumor Oxygenation as Detected by Near-Infrared Spectroscopy in Colon Carcinoma in Mice."