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2- fluoro- 6- (6- hydroxynaphthalen- 2- yl)pyridin- 3- ol

a ligand of estrogen receptor beta; structure in first source

Also Known As:

18F-FHNP; 2-18F-fluoro-6-(6-hydroxynaphthalen-2-yl)pyridin-3-ol

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthalenes: 18
        Naphthols: 64
        2-fluoro-6-(6-hydroxynaphthalen-2-yl)pyridin-3-ol: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthalenes: 18
    - Naphthols: 64
      - 2-fluoro-6-(6-hydroxynaphthalen-2-yl)pyridin-3-ol: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - 2-fluoro-6-(6-hydroxynaphthalen-2-yl)pyridin-3-ol: 2

Experts

1.	Antunes, Inês F: 2 articles (11/2017 - 04/2017)
2.	Dierckx, Rudi A J O: 2 articles (11/2017 - 04/2017)
3.	Hospers, Geke A P: 2 articles (11/2017 - 04/2017)
4.	de Vries, Elisabeth G E: 2 articles (11/2017 - 04/2017)
5.	de Vries, Erik F J: 2 articles (11/2017 - 04/2017)
6.	van Waarde, Aren: 2 articles (11/2017 - 04/2017)
7.	Boerema, Ate S: 1 article (11/2017)
8.	Glaudemans, Andor W J M: 1 article (11/2017)
9.	Sijbesma, Jurgen W A: 1 article (11/2017)
10.	Willemsen, Antoon T M: 1 article (11/2017)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2017 - "18F-FES showed a 2-fold-higher tumor uptake than 18F-FHNP. " 04/01/2017 - "Both 18F-FHNP and 18F-FES PET could clearly visualize the tumor in male mice bearing a SKOV3 xenograft. " 11/01/2017 - "A reduction in 18F-FHNP tumor uptake and Ki values was observed in the presence of estradiol or genistein. " 11/01/2017 - "Two weeks after tumor inoculation, a dynamic 18F-FHNP PET scan with arterial blood sampling was acquired from rats treated with vehicle or various concentrations of estradiol (nonspecific ER agonist) or genistein (ERβ-selective agonist). " 04/01/2017 - "The tumor-to-plasma ratio of 18F-FHNP decreased 41% (P = 0.004) and 64% (P = 0.0009) when administered with estradiol and genistein, respectively. "
2.	Carcinoma (Carcinomatosis) 04/01/2017 - "In vitro affinity of 18F-FHNP and 18F-FES for ER was evaluated in SKOV3 ovarian carcinoma cells. "

Related Drugs and Biologics

1.	Genistein
2.	Estradiol (Delestrogen)