Polonium-210

11/01/1977 - "Histochemical, light and electron microscopic study of polonium-210 induced peripheral tumors in hamster lungs: evidence implicating the Clara cell as the cell of origin."
12/03/2020 - "Alpha radiation from Polonium-210 (210Po) is considered to be an important agent of bronchial cancer in smokers. "
05/01/2009 - "A distinguished group of speakers discussed topics that included (i) non-targeted effects of radiation, (ii) exposure to high natural background radiation, (iii) non-cancer effects in Japanese bomb survivors, (iv) lessons learnt from Chernobyl, (v) radiation in the workplace, (vi) biokinetic modelling, (vii) uncertainties in risk estimation, (viii) issues in diagnostic medical exposures, (ix) lessons leant from the polonium-210 incidence and (x) how the radiobiology/radiation oncology community is needed to help society prepare for potential future acts of radiation terrorism. "
03/26/1966 - "Cigarettes, cancer and polonium-210."
06/01/1980 - "Polonium-210 was found to be deposited in the fibrous thickening of the alveolus around the subpleural fibrotic lesion, bronchial epithelium, and peribronchial lymph apparati at the initial period of administration of polonium-210, but during the period of pulmonary carcinogenesis, it was deposited in the localized fibrotic lesion in the lung and in a few cancer cells. "

05/16/1975 - "Lung cancers have been induced in 9 to 53 percent of hamsters given multiple intratracheal instillations of polonium-210 in amounts yielding lifetime exposures of 15 to 300 rads to the lungs. "
05/16/1975 - "Lung cancer induced in hamsters by low doses of alpha radiation from polonium-210."
12/23/2020 - "Polonium-210 levels were significantly higher in COPD versus no COPD patients (median value: 3.60 vs. 0.97 mBq; p = 0.007); former and current smokers, without and with COPD, had significantly increased polonium-210 levels (p = 0.012); 96% of confirmed versus 69% of non-confirmed lung cancer patients recorded detectable polonium-210 levels (p = 0.018). "
12/23/2020 - "The main aim of this "Polonium in vivo" study was to evaluate polonium-210 radioactivity in bronchopulmonary systems of smoker, ex-smoker and never smoker patients with suspected lung cancer. "
12/23/2020 - "The "Polonium In Vivo" Study: Polonium-210 in Bronchial Lavages of Patients with Suspected Lung Cancer."

03/01/1986 - "The findings from this study, the biologic activity of snuff in animal models, and the epidemiologic studies on snuff use and oral cancer strongly suggest the need for reduction of carcinogens and especially of nitrosamines and polonium-210 in snuff."

08/27/2023 - "Ingestion of polonium-210 from environmental media and food can cause serious health hazards (e.g., gastrointestinal symptoms, tumours, etc.) and has been a public health concern worldwide since the 2006 poisoning of Agent Litvinenko 210Po in Russia. "
12/01/2017 - "Mr Litvinenko died on 23 November 2006, having been poisoned with polonium-210 on 1 November, with evidence of a previous poisoning attempt during October 2006. "
12/01/2017 - "Collateral contamination concomitant to the polonium-210 poisoning of Mr Alexander Litvinenko."
03/20/2017 - "The polonium-210 poisoning of Mr Alexander Litvinenko."
09/10/2016 - "Polonium-210 ((210)Po) gained widespread notoriety after the poisoning and subsequent death of Mr Alexander Litvinenko in London, UK, in 2006. "

10/01/1975 - "Several cell lines designated HLAC were derived from primary lung carcinomas induced in Syrian hamsters by polonium-210 or benzo[a]pyrene. "
06/01/1980 - "It was subsequently found that lung carcinoma was induced in close proximity to the localized pulmonary fibrosis in 3 of 26 rats (11.5%) during the period from completion of the 15 weekly administrations of polonium-210 until the end of this experiment (21 months after the 1st instillation of polonium-210). "