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fluorenyl-9-methoxycarbonyl diphenylalanine

structure in first source

Also Known As:

Fmoc-FF; Fmoc-Phe-Phe

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - Dipeptides: 945
      - fluorenyl-9-methoxycarbonyl diphenylalanine: 2
Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Fluorenes: 7
        fluorenyl-9-methoxycarbonyl diphenylalanine: 2
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Fluorenes: 7
    - fluorenyl-9-methoxycarbonyl diphenylalanine: 2

Experts

1.	Braet, Filip: 1 article (02/2015)
2.	Gloria, Danmar: 1 article (02/2015)
3.	Su, Yingying: 1 article (02/2015)
4.	Thordarson, Pall: 1 article (02/2015)
5.	Truong, Warren Ty: 1 article (02/2015)

Related Diseases

1.	Colorectal Neoplasms (Colorectal Cancer) 02/01/2015 - "In addition, the effect of chemotherapeutics (5-fluorouracil and paclitaxel) released from the Fmoc-FF gel (with addition before and after gelation) on colorectal cancer cells were investigated using this methodology, demonstrating enhanced activity of these drugs compared to bulk control. "
2.	Neoplasms (Cancer) 03/22/2023 - "The specificity of the machinery used by Fmoc-FF nanogels confers a selectivity toward cancer cell lines overexpressing the protein caveolin1 and efficiently performing caveolae-mediated endocytosis." 03/22/2023 - "Fmoc-FF nanogels, endowed with a diameter of ~130 nm and a zeta potential of ~-20.0/-25.0 mV, enter cancer cells via caveolae, mostly those responsible for albumin uptake. "
3.	Breast Neoplasms (Breast Cancer) 03/22/2023 - "Cells viability of Fmoc-FF nanogels was evaluated by MTT assay on six breast cancer cell lines at different incubation times (24, 48, and 72 h) and peptide concentrations (in the range 6.25 × 10-4 ÷ 5·10-3 × wt%). " 03/22/2023 - "Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines."

Related Drugs and Biologics

1.	Caveolins
2.	Paclitaxel (Taxol)
3.	Proteins (Proteins, Gene)
4.	Peptides (Polypeptides)
5.	Fluorouracil (Carac)
6.	Albumins
7.	Nanogels