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curzerene

from the aerial parts of Smyrnium perfoliatum subsp. perfoliatum; structure in first source

Networked: 7 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Sesquiterpenes: 1370
      - curzerene: 7

Experts

1.	Cao, Yuanyuan: 1 article (01/2022)
2.	Cheng, Bo: 1 article (01/2022)
3.	Gao, Dianshuai: 1 article (01/2022)
4.	Hong, Xiaoliang: 1 article (01/2022)
5.	Qin, Dengli: 1 article (01/2022)
6.	Wang, Linfang: 1 article (01/2022)
7.	Zhou, Han: 1 article (01/2022)
8.	Alireza, Rangin: 1 article (09/2019)
9.	Naser, Abbasi: 1 article (09/2019)
10.	Pari, Nazari: 1 article (09/2019)

Related Diseases

1.	Seizures (Absence Seizure) 07/01/2017 - "It seems that SCEO and curzerene are useful for the treatment of absence seizure and this effect may be related to their effects on GABAergic and opioid systems."
2.	Coccidiosis 12/01/2010 - "Efficacy of volatile oils (curzerene, furanoeudesma-1, 3-diene and lindestrene) on avian coccidiosis under laboratory conditions."
3.	Glioma (Gliomas) 01/01/2022 - "The purpose of this study was to clarify the effect of curzerene on glioma progression and further explore its potential mechanism. " 01/01/2022 - "Curzerene can inhibit the progression of non-small-cell lung cancer, but its role in glioma has not been reported. " 01/01/2022 - "The expression of glutathione S-transferase A4 (GSTA4) in glioblastoma and the effect of curzerene on the expression of GSTA4 and matrix metalloproteinase 9 and the activation of the mTOR pathway were detected by Western blotting and RT-PCR, and the effects of curzerene treatment on glioma malignant character were detected by cell biological assays. "
4.	Neoplasms (Cancer) 01/01/2022 - "In vivo, curzerene was found to significantly inhibit tumor growth in nude mice and to prolong the survival time of tumor-bearing nude mice. " 01/01/2017 - "Tumor growth was significantly inhibited in SPC-A1 cell-bearing nude mice by using curzerene (135 mg/kg daily), meanwhile, curzerene did not significantly affect body mass and the organs of the mice, which may indicate that curzerene has limited toxicity and side effects in vivo. " 03/25/2019 - "Antiproliferative effects of the oils and curzerene were tested against colon (HCT-116), gastric (AGP-01), and melanoma (SKMEL-19) human cancer cell lines and a normal human fibroblast cell line (MRC-5), using MTT assay. "
5.	Weight Loss (Weight Reduction) 09/30/2019 - "Curzerene and SE reduced the mean of weight loss, diarrhea, and wet dog shakes in morphine-dependent mice in comparison with clonidine. "

Related Drugs and Biologics

1.	Volatile Oils (Essential Oils)
2.	Opioid Analgesics (Opioids)
3.	Matrix Metalloproteinase 9 (Gelatinase B)
4.	Oils
5.	Morphine (MS Contin)
6.	Glutathione Transferase (Glutathione S-Transferase)
7.	Dimethyl Sulfoxide (DMSO)
8.	Clonidine (ST 155)
9.	zingiberene
10.	camphene