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hylin

a hyaluronan export inhibitor; structure in first source

Also Known As:

1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kang, Hee Kyoung: 1 article (08/2022)
2.	Kim, Min Kyung: 1 article (08/2022)
3.	Park, Eunji: 1 article (08/2022)
4.	Park, Hee Joo: 1 article (08/2022)
5.	Park, Yoonkyung: 1 article (08/2022)
6.	Cao, Jing: 1 article (11/2017)
7.	Lei, Jing: 1 article (11/2017)
8.	Liu, Fei: 1 article (11/2017)
9.	Liu, Hongrui: 1 article (11/2017)
10.	Shan, Yanke: 1 article (11/2017)

Related Diseases

1.	Hemolysis 11/01/2017 - "In this study, we designed a nano-system where a novel antibacterial peptide RGD-hylin a1 with reduced hemolysis than the commonly studied melittin was loaded onto mesoporous silica (HMS). "
2.	Neoplasms (Cancer) 11/01/2017 - "When this nano-system was administered to tumor-bearing mice at low dosage via intravenous injection, the growth of the solid tumor was blocked by the RGD-hylin a1-HMS nano-system with a 50-60% inhibition rate relative to the PBS-treated control group in terms of tumor volume and weight. "
3.	Melanoma (Melanoma, Malignant) 09/01/2010 - "This paper describes a new method for the preparation of 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one 1 and its derivatives 2-5. This set of synthetic compounds exhibited high antitumoral activities regarding in vitro screening against several human tumor cell lines as lung carcinoma NCI-460, melanoma UACC-62, breast MCF-7, colon HT-29, renal 786-O, ovarian OVCAR-03 and ovarian expressing the resistance phenotype for adriamycin NCI-ADR/RES, prostate PC-3, and leukemia K-562. "
4.	Leukemia 09/01/2010 - "This paper describes a new method for the preparation of 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one 1 and its derivatives 2-5. This set of synthetic compounds exhibited high antitumoral activities regarding in vitro screening against several human tumor cell lines as lung carcinoma NCI-460, melanoma UACC-62, breast MCF-7, colon HT-29, renal 786-O, ovarian OVCAR-03 and ovarian expressing the resistance phenotype for adriamycin NCI-ADR/RES, prostate PC-3, and leukemia K-562. "
5.	Inflammation (Inflammations) 08/01/2022 - "Hylin a1-11K and Hylin a1-15K reduced inflammation by suppressing pro-inflammatory cytokines expression by A. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Silicon Dioxide (Silica)
3.	Melitten (Melittin)
4.	Cytokines
5.	Doxorubicin (Adriamycin)
6.	Antimicrobial Peptides

Related Therapies and Procedures

1.	Intravenous Injections