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5,8- dihydroxy- 10- methoxy- 2- propylbenzo(h)chromen- 4- one

has analgesic and anti-inflammatory activities; isolated from Comanthus bennetti; structure in first source

Also Known As:

comaparvin

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        5,8-dihydroxy-10-methoxy-2-propylbenzo(h)chromen-4-one: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        5,8-dihydroxy-10-methoxy-2-propylbenzo(h)chromen-4-one: 2

Experts

1.	Chen, I-Ming: 1 article (09/2014)
2.	Chen, Li-Chai: 1 article (09/2014)
3.	Chen, Wu-Fu: 1 article (09/2014)
4.	Jang, Ing-Yang: 1 article (09/2014)
5.	Jean, Yen-Hsuan: 1 article (09/2014)
6.	Lin, Yen-You: 1 article (09/2014)
7.	Lu, Yi: 1 article (09/2014)
8.	Sheu, Jyh-Horng: 1 article (09/2014)
9.	Su, Jui-Hsin: 1 article (09/2014)
10.	Sung, Ping-Jyun: 1 article (09/2014)

Related Diseases

1.	Pain (Aches) 09/16/2014 - "These results suggest that comaparvin is a potential anti-inflammatory therapeutic agent against inflammatory pain. "
2.	Neoplasms (Cancer) 04/25/2011 - "Furthermore, comaparvin sensitized cancer cells to apoptotic effects mediated by the pro-inflammatory cytokine TNF-α. "
3.	Inflammation (Inflammations) 09/16/2014 - "Moreover, our results showed that post-treatment with comaparvin significantly inhibited mechanical allodynia, thermal hyperalgesia and weight-bearing deficits in rats with carrageenan-induced inflammation. "
4.	Hyperalgesia 09/16/2014 - "Moreover, our results showed that post-treatment with comaparvin significantly inhibited mechanical allodynia, thermal hyperalgesia and weight-bearing deficits in rats with carrageenan-induced inflammation. "
5.	Hepatocellular Carcinoma (Hepatoma) 04/25/2011 - "From these compounds only two naphthopyrones, comaparvin and 6-methoxycomaparvin exhibited noteworthy inhibitory activity against tumor necrosis factor-alpha (TNF-α) induced NF-κB activation in rat hepatoma cells and human breast cancer cells. "

Related Drugs and Biologics

1.	Cytokines
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Carrageenan
4.	6-methoxycomaparvin