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tert-dodecane S-nitrosothiol

a nitric oxide donor; structure in first source

Also Known As:

tDodSNO

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Nitroso Compounds: 446
  - Reactive Nitrogen Species: 731
    - S-Nitrosothiols: 186
      - tert-dodecane S-nitrosothiol: 1
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - S-Nitrosothiols: 186
      - tert-dodecane S-nitrosothiol: 1

Experts

1.	Alimoradi, Houman: 1 article (01/2018)
2.	Alshaibani, Lama: 1 article (01/2018)
3.	Barzegar-Fallah, Anita: 1 article (01/2018)
4.	Greish, Khaled: 1 article (01/2018)
5.	Pittalà, Valeria: 1 article (01/2018)

Related Diseases

1.	Triple Negative Breast Neoplasms 01/01/2018 - "Effects of SMA-tDodSNO and/or in combination with Dox or SMA-Dox on cell viability, apoptosis, mitochondrial membrane potential, lysosomal membrane permeability, tumor tissue, and tumor growth were studied using in vitro and in vivo model of triple-negative breast cancer (TNBC). "
2.	Neoplasms (Cancer) 01/01/2018 - "Subcutaneous administration of SMA-tDodSNO (1 mg/kg) to xenografted mice bearing 4T1 cells showed that SMA-tDodSNO alone caused a twofold decrease in the tumor size compared to the control group. " 01/01/2018 - "In addition, the concentrations of SMA-Dox and Dox in combination with SMA-tDodSNO were measured in cells and tumor tissues. " 01/01/2018 - "SMA-tDodSNO in combination with SMA-Dox resulted in a statistically significant 4.7-fold reduction in the tumor volume (P<0.001 vs control), without causing significant toxicity as monitored through body weight loss. " 01/01/2018 - "Effects of SMA-tDodSNO and/or in combination with Dox or SMA-Dox on cell viability, apoptosis, mitochondrial membrane potential, lysosomal membrane permeability, tumor tissue, and tumor growth were studied using in vitro and in vivo model of triple-negative breast cancer (TNBC). "
3.	Body Weight (Weight, Body) 01/01/2018 - "SMA-tDodSNO in combination with SMA-Dox resulted in a statistically significant 4.7-fold reduction in the tumor volume (P<0.001 vs control), without causing significant toxicity as monitored through body weight loss. "