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poly(lactic acid)-poly(ethylene glycol)-poly(lysine)

used for gene delivery; structure in first source

Also Known As:

PLA-PEG-PLL

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Chen, Zhijin: 1 article (08/2011)
2.	Liu, Chunxi: 1 article (08/2011)
3.	Liu, Yongjun: 1 article (08/2011)
4.	Lu, Zaijun: 1 article (08/2011)
5.	Yu, Dexin: 1 article (08/2011)
6.	Zhang, Na: 1 article (08/2011)

Related Diseases

1.	Neoplasms (Cancer) 08/01/2011 - "These results demonstrated that this novel MRI contrast agent Anti-VEGF PLA-PEG-PLL-Gd NPs showed great potential in the early diagnosis of liver tumors." 08/01/2011 - "Here, we designed a novel multifunctional polymeric nanoparticle contrast agent (Anti-VEGF PLA-PEG-PLL-Gd NP) simultaneously modified with Gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and anti-vascular endothelial growth factor (VEGF) antibody to deliver Gd-DTPA to the tumor area and achieve the early diagnosis of hepatocellular carcinoma (HCC). "
2.	Hepatocellular Carcinoma (Hepatoma) 08/01/2011 - "The Anti-VEGF PLA-PEG-PLL-Gd NPs exhibited high T(1) relaxivity and no obvious cytotoxicity under the experimental concentrations in human hepatocellular carcinoma (HepG2) cells. " 08/01/2011 - "Here, we designed a novel multifunctional polymeric nanoparticle contrast agent (Anti-VEGF PLA-PEG-PLL-Gd NP) simultaneously modified with Gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA) and anti-vascular endothelial growth factor (VEGF) antibody to deliver Gd-DTPA to the tumor area and achieve the early diagnosis of hepatocellular carcinoma (HCC). "

Related Drugs and Biologics

1.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
2.	Gadolinium DTPA (Magnevist)
3.	Gadolinium
4.	Pentetic Acid (DTPA)
5.	Contrast Media