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4- (6- hydroxy- 7- tricyclo(3.3.1.13,7)dec- 1- yl- 2- naphthalenyl)benzoic acid

an agonist of retinoic acid receptor gamma; structure in first source

Also Known As:

CD1530

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ausubel, Frederick M: 1 article (01/2018)
2.	Conery, Annie L: 1 article (01/2018)
3.	Fricke, Nico: 1 article (01/2018)
4.	Fuchs, Beth Burgwyn: 1 article (01/2018)
5.	Gao, Huajian: 1 article (01/2018)
6.	Gilmore, Michael S: 1 article (01/2018)
7.	Hendricks, Gabriel Lambert: 1 article (01/2018)
8.	Keohane, Colleen E: 1 article (01/2018)
9.	Kim, Wooseong: 1 article (01/2018)
10.	Lee, Kiho: 1 article (01/2018)

Related Diseases

1.	Carcinogenesis 06/17/2014 - "The major reduction in 4-HNE staining in the retinoid treatment groups suggests a novel mechanism of action, reduction of ROS, by which bexarotene and CD1530 inhibit carcinogenesis. " 06/17/2014 - "Combination of bexarotene and the retinoid CD1530 reduces murine oral-cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide." 06/17/2014 - "We investigated the effects of bexarotene (a retinoid X receptor agonist), CD1530 (a retinoic acid receptor γ selective agonist), and the combination of these two drugs for the prevention of oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide (4-NQO) in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma previously generated in our laboratory. "
2.	Infections 01/01/2018 - "Here we used a Caenorhabditis elegans-MRSA infection screen to identify two synthetic retinoids, CD437 and CD1530, which kill both growing and persister MRSA cells by disrupting lipid bilayers. "
3.	Esophageal Squamous Cell Carcinoma 06/17/2014 - "We investigated the effects of bexarotene (a retinoid X receptor agonist), CD1530 (a retinoic acid receptor γ selective agonist), and the combination of these two drugs for the prevention of oral carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide (4-NQO) in a mouse model of human oral-cavity and esophageal squamous-cell carcinoma previously generated in our laboratory. "

Related Drugs and Biologics

1.	Retinoids
2.	Retinoid X Receptors (Retinoid X Receptor)
3.	Retinoic Acid Receptors (Retinoic Acid Receptor)
4.	Lipid Bilayers (Lipid Bilayer)
5.	Carcinogens
6.	Bexarotene (LGD1069)