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dihydroaustrasulfone alcohol

has both anti-inflammatory and antineoplastic activities; structure in first source

Also Known As:

WA-25 compound

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Ketones: 2618
  - Butanones
    - dihydroaustrasulfone alcohol: 7
- Sulfur Compounds: 278
  - Sulfones: 534
    - dihydroaustrasulfone alcohol: 7

Experts

1.	Sheu, Jyh-Horng: 5 articles (01/2018 - 12/2010)
2.	Wen, Zhi-Hong: 4 articles (01/2018 - 12/2010)
3.	Chen, Chun-Hong: 2 articles (01/2018 - 04/2015)
4.	Chen, Wu-Fu: 2 articles (01/2018 - 04/2015)
5.	Hung, Han-Chun: 2 articles (01/2018 - 04/2015)
6.	Pan, Chun-Hsu: 2 articles (05/2015 - 01/2014)
7.	Wu, Chieh-Hsi: 2 articles (05/2015 - 01/2014)
8.	Feng, Chien-Wei: 1 article (01/2018)
9.	Lin, Yen-You: 1 article (01/2018)
10.	Pan, Chieh-Yu: 1 article (01/2018)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2023 - "Dihydroaustrasulfone alcohol (DA), the synthetic precursor of a natural compound (austrasulfone) isolated from the coral species Cladiella australis, has shown cytotoxic effects against cancer cells. " 05/15/2015 - "Dihydroaustrasulfone alcohol (DA), an active compound firstly isolated from marine corals, has been reported to reveal anti-cancer and anti-inflammation activities. " 01/09/2014 - "We concluded that dihydroaustrasulfone alcohol is a new pure compound with anti-migration and anti-tumor growth activity in lung cancer and might be applied to clinical treatment in the future. " 01/09/2014 - "Furthermore, dihydroaustrasulfone alcohol markedly inhibited tumor growth in Lewis lung cancer (LLC)-bearing mice. " 01/09/2014 - "Dihydroaustrasulfone alcohol, which is isolated from marine coral, has shown antioxidant activity, but has not been reported to have an anti-cancer effect. "
2.	Neointima 04/17/2015 - "Although dihydroaustrasulfone alcohol has been shown to inhibit neointima formation, its effect on human vascular smooth muscle cells (VSMCs) has not been elucidated. " 02/06/2015 - "WA-25 (dihydroaustrasulfone alcohol, a synthetic derivative of marine compound WE-2) suppresses atherosclerosis in rats by reducing neointima formation. "
3.	Atherosclerosis 02/06/2015 - "WA-25 (dihydroaustrasulfone alcohol, a synthetic derivative of marine compound WE-2) suppresses atherosclerosis in rats by reducing neointima formation. " 12/01/2010 - "Dihydroaustrasulfone alcohol (3), the synthetic precursor of 1, not only exhibited in vitro anti-inflammatory activity, but also showed potent therapeutic ability in the treatment of neuropathic pain, atherosclerosis, and multiple sclerosis in rats."
4.	Lewis Lung Carcinoma 01/09/2014 - "Inhibitory effect of dihydroaustrasulfone alcohol on the migration of human non-small cell lung carcinoma A549 cells and the antitumor effect on a Lewis lung carcinoma-bearing tumor model in C57BL/6J mice."
5.	Neuralgia (Stump Neuralgia) 12/01/2010 - "Dihydroaustrasulfone alcohol (3), the synthetic precursor of 1, not only exhibited in vitro anti-inflammatory activity, but also showed potent therapeutic ability in the treatment of neuropathic pain, atherosclerosis, and multiple sclerosis in rats."

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