[Intravenous immunoglobulin in combined therapy for children with juvenile rheumatoid arthritis (evaluation of therapeutical efficiency and factors that influence them)].

Abstract

The study was based on the follow-up of 20 patients with systemic juvenile rheumatoid arthritis who received intravenous immunoglobulin. The study comparatively analyzed the efficiency of the therapy alone and in combination with steroids. The immunoglobulin was shown to have positive effects on both articular and extraarticular manifestations of the disease particularly in a group of children untreated with corticosteroids. The duration of the disease did not affect the therapeutical properties of immunoglobulin.

• Authors: A V Shaĭkov, I O Kuznetsova, G R Movsisian
• Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk (Vestn Ross Akad Med Nauk) Issue 12 Pg. 36-9 ( 1998) ISSN: 0869-6047 [Print] Russia (Federation)
• Vernacular Title: Vnutrivennoe vvedenie immunoglobulina v kompleksnoĭ terapii deteĭ s iuvenil'nym revmatoidnym artritom (otsenka terapevticheskoĭ éffektivnosti i vliiaiushchikh na nee faktorov).
• PMID: 9987958 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Glucocorticoids
• Immunoglobulins, Intravenous

Topics

• Adolescent
• Arthritis, Juvenile (therapy)
• Child
• Child, Preschool
• Drug Therapy, Combination
• Female
• Follow-Up Studies
• Glucocorticoids (therapeutic use)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Male
• Patient Satisfaction
• Surveys and Questionnaires
• Treatment Outcome