Successful treatment of cornual pregnancy with 1-day high-dose methotrexate regimen and folinic acid rescue.

Abstract

This report describes a woman with a cornual pregnancy, documented by laparoscopy and ultrasonography, who was successfully treated with a 1-day high-dose methotrexate regimen and folinic acid rescue. The serum beta-hCG level was 2,260 and increased to 3,060 IU/l on the 5th day after treatment before it fell precipitously to below 250 IU/l 15 days after methotrexate treatment. No side effects were experienced by the patient.

• Authors: R Talmon, S Filmar, J Itskovitz-Eldor
• Journal: Gynecologic and obstetric investigation (Gynecol Obstet Invest) Vol. 35 Issue 4 Pg. 243-4 ( 1993) ISSN: 0378-7346 [Print] Switzerland
• PMID: 7687231 (Publication Type: Case Reports, Journal Article)

Chemical References

• Chorionic Gonadotropin
• Chorionic Gonadotropin, beta Subunit, Human
• Peptide Fragments
• Leucovorin
• Methotrexate

Topics

• Adult
• Chorionic Gonadotropin (blood)
• Chorionic Gonadotropin, beta Subunit, Human
• Female
• Humans
• Leucovorin (administration & dosage, therapeutic use)
• Methotrexate (administration & dosage, therapeutic use)
• Peptide Fragments (blood)
• Pregnancy
• Pregnancy, Tubal (blood, diagnostic imaging, drug therapy)
• Ultrasonography