An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Also Known As:
Mexate; Methotrexate Hydrate; Methotrexate Sodium; Methotrexate, (D)-Isomer; Methotrexate, (DL)-Isomer; Methotrexate, Dicesium Salt; Methotrexate, Disodium Salt; Methotrexate, Sodium Salt; Dicesium Salt Methotrexate; Hydrate, Methotrexate; Sodium, Methotrexate; Amethopterin; L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-