[Pharmacotherapeutic use of antipruritic drugs in skin diseases].

Abstract

Pruritus is a predominant and serious phenomenon of various skin diseases. As mediators of pruritus, histamine, serotonin (hydroxytryptamine), eicosanoids, neuropeptides, cytokines and proteases are known. The symptomatic treatment of pruritus is variable. Glucocorticoids are well known antipruritic drugs. H1-antihistaminics are used frequently. But the efficacy of these drugs is questionable in dogs. Additionally, mast cell stabilisators, unsaturated fatty acids (i. e. primrose oil, fish oil) and other antipruritic agents (local anesthetics) are used.

• Authors: M Kietzmann
• Journal: Tierarztliche Praxis (Tierarztl Prax) Vol. 23 Issue 3 Pg. 218-23 (Jun 1995) ISSN: 0303-6286 [Print] Germany
• Vernacular Title: Pharmakotherapeutische Ansatzpunkte zur Juckreizlinderung bei Hauterkrankungen.
• PMID: 7545832 (Publication Type: Journal Article, Review)

Chemical References

• Anesthetics, Local
• Anti-Inflammatory Agents, Non-Steroidal
• Antipruritics
• Cytokines
• Eicosanoids
• Fatty Acids, Essential
• Fish Oils
• Glucocorticoids
• Linoleic Acids
• Neuropeptides
• Plant Oils
• Serotonin
• evening primrose oil
• gamma-Linolenic Acid
• Endopeptidases

Topics

• Anesthetics, Local (therapeutic use)
• Animals
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• Antipruritics (therapeutic use)
• Cytokines (physiology)
• Eicosanoids (physiology)
• Endopeptidases (physiology)
• Fatty Acids, Essential (therapeutic use)
• Fish Oils (therapeutic use)
• Glucocorticoids (therapeutic use)
• Histamine Release
• Linoleic Acids
• Neuropeptides (physiology)
• Oenothera biennis
• Plant Oils
• Pruritus (drug therapy, physiopathology, veterinary)
• Serotonin (physiology)
• Skin Diseases (drug therapy, physiopathology, veterinary)
• gamma-Linolenic Acid