The role of IL-17 in lung cancer growth.

Abstract

Interleukin 17 (IL-17) is an inflammatory cytokine with multiple roles in immune protection, immunopathology, and inflammation-related tumors. Lung cancer is inflammation-related cancer, and a large number of studies have shown that IL-17 contributes to the metastasis and progression of lung cancer. However, some studies have shown that IL17 inhibits the occurrence of lung cancer. At present, there is still some controversy about the role of IL17 in the occurrence and development of lung cancer. This review introduces the basic characteristics of IL-17 and focuses on its role in lung cancer, in order to provide a certain theoretical basis for the prevention, diagnosis, and treatment of lung cancer.

• Authors: Liping Liu, Renli Liu, Chaojie Wei, Dong Li, Xiuzhu Gao
• Journal: Cytokine (Cytokine) Vol. 169 Pg. 156265 (09 2023) ISSN: 1096-0023 [Electronic] England
• PMID: 37348188 (Publication Type: Journal Article, Review, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2023 Elsevier Ltd. All rights reserved.

Chemical References

• Interleukin-17
• Cytokines

Topics

• Humans
• Interleukin-17
• Lung Neoplasms (pathology)
• Cytokines
• Inflammation