Inadvertent filtering bleb due to extracapsular cataract extraction wound reopening after mitomycin C use: a case report.

Abstract

BACKGROUND:

 Mitomycin C has been used adjunctively in various procedures, including pterygium excision. Delayed wound healing, the long-term complication of mitomycin C, can occur several years later and may rarely cause a subsequent inadvertent filtering bleb. However, conjunctival bleb formation from the reopening of an adjacent surgical wound after mitomycin C use has not been reported.

CASE PRESENTATION:

A 91-year-old Thai woman had undergone pterygium excision 26 years ago, with adjunctive mitomycin C, as well as an uneventful extracapsular cataract extraction in the same year. The patient developed a filtering bleb without glaucoma surgery or trauma approximately 25 years later. Anterior segment ocular coherence tomography illustrated a fistula connected between the bleb and anterior chamber at the scleral spur. The bleb was observed without further management, as no hypotony or bleb-related complications occurred. The symptoms/signs of bleb-related infection were advised.

CONCLUSIONS:

 This is a case report of a rare novel complication of mitomycin C application. Conjunctival bleb formation from the reopening of surgical wound, which was related to the previous mitomycin C use, could occur after a few decades.

• Authors: Phit Upaphong, Kessara Pathanapitoon, Winai Chaidaroon
• Journal: Journal of medical case reports (J Med Case Rep) Vol. 17 Issue 1 Pg. 57 (Feb 18 2023) ISSN: 1752-1947 [Electronic] England
• PMID: 36800977 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2023. The Author(s).

Chemical References

• Mitomycin

Topics

• Aged, 80 and over
• Female
• Humans
• Cataract Extraction (adverse effects)
• Glaucoma (surgery)
• Mitomycin (adverse effects)
• Postoperative Complications (surgery)
• Pterygium (complications, surgery)
• Surgical Wound (complications, surgery)
• Trabeculectomy