Fistula

01/01/2022 - "In the subsequent step, treatment with fibrin glue resulted in complete closure of the fistula. The complementary use of fibrin glue may be effective in the treatment of small oesophagojejunostomy leakages when other endoscopic methods are not sufficient."
03/01/2001 - "Fibrin glue is simple and effective treatment for all anal fistulas with excellent functional results."
11/30/2023 - "In addition, use of interpositional flaps, trimming fistula edges, fibrin glue, and fascial sling did not show significant improvement in rates of fistula cure. "
12/01/2008 - "Closing the bronchial stump with an appropriate technique and supporting it with fibrin glue were considered effective in preventing bronchopleural fistula development after pulmonary resection in high-risk patients."
12/01/2002 - "Fibrin glue is a novel treatment for anal fistulas and possesses many advantages in the treatment of difficult high fistulas. "

06/01/2008 - "The aims of this study were to evaluate the efficacy of combined treatment with infliximab and setons for complex perianal fistulas in CD and to define the optimal time for seton removal by anal endosonography (AE). "
01/01/2013 - "Treatment with infliximab was followed by perianal fistula closure with marked improvement in the quality of life over 2-year follow-up period."
08/12/2020 - "Furthermore, improvements of life quality, body image and self-esteem were significantly greater in patients with perianal fistula who were than were not treated with infliximab (P<0.05 each). "
12/01/2008 - "A retrospective 1-year review was undertaken of all CD patients with successfully induced remission or fistula closure with 3 infusions of infliximab. "
04/01/2015 - "This study aimed to assess the efficacy of local surgery combined with infliximab on sustained fistula closure and to identify predictive factors for response after this combined treatment. "

01/01/2010 - "Pooling of data showed that immunoregulators and antibiotics are significantly effective for at least a 50% reduction from baseline in the number of open actively draining fistulas with relative risk (RR) of 2.57 (95% CI of 1.55-4.25, P=0.0003) in four trials and 2.05 (95% CI of 1.03-4.08, P= 0.0414) in two trials respectively. "
09/01/2021 - "No antibiotic was administered and one week later, 50% of the fistulas were closed with a significant improvement of the patient's clinical condition. "
01/01/2018 - "Antibiotic oral pack was effective in reducing the rate of oronasal fistula in patients undergoing cleft palatoplasty."
10/01/1990 - "From these findings, we consider that the results of one stage operation can be improved by applying pedicle muscle plombage for closure of fistula after the initial operation following treatment with effective antibiotics.(ABSTRACT TRUNCATED AT 250 WORDS)"
11/01/2017 - "In the regression analysis postoperative antibiotic use remained protective against fistula development (odds ratio = 0.371; confidence interval, 0.196-0.703), furthermore male sex presented as a risk factor for developing fistula in-ano (odds ratio = 3.11; confidence interval, 1.31-7.38). "

04/01/2006 - "We report a new case of thoracic duct injury effectively treated by octreotide, leading to an early decrease in drainage and early fistula closure with minimal adverse effects. "
12/01/2000 - "We conclude that octreotide is effective in treating thoracic duct injury, leading to an early decrease in drainage and early fistula closure. "
08/01/2015 - "In these patients, octreotide was safe and effective in resolving neck chylous fistulas. "
08/01/2015 - "To evaluate the efficacy of octreotide for use in patients with postoperative chyle fistulas. "
01/01/1994 - "[Efficacy of octreotide acetate in the treatment of a pancreatic-pleural fistula. "

06/21/2022 - "Thirty-seven (77%) patients on maintenance adalimumab achieved fistula healing and 17 (35.4%) achieved fistula closure. "
01/01/2021 - "To evaluate the clinical and ultrasound features related with both healing and persistence of fistulous tracts in patients under treatment with adalimumab, a retrospective analysis of power-Doppler ultrasound (PD-US) images with fistulas in HS patients was performed. "
01/01/2020 - "For adalimumab, receiver operator characteristic analysis identified an optimum level of >6.8 μg/mL and >9.8 μg/mL for fistula healing and closure, respectively. "
08/01/2015 - "Negative predictors included present perianal fistula (HR, 0.39; 95% CI, 0.16-0.98) and prior primary nonresponse to adalimumab (ADA; HR relative to secondary loss of response, 0.18; 95% CI, 0.04-0.76). "
11/01/2013 - "Fistula healing was assessed in adalimumab-randomised patients with fistula at baseline. "

02/16/2017 - "The formation of multiple perforations and fistulas following high dosage steroid administration can have a good outcome with appropriate management. "
10/26/2016 - "Outcomes of interest included: clinical remission, clinical improvement, fistula improvement or healing, steroid sparing, adverse events, withdrawals due to adverse events and serious adverse events. "
04/30/2013 - "Outcomes of interest included: clinical remission, clinical improvement, fistula improvement or healing, steroid sparing, adverse events, withdrawals due to adverse events and serious adverse events. "
03/01/2022 - "This study aims to assess outcomes and safety of steroid use in Furlow palatoplasty and determine its impact on fistula formation. "
07/01/1998 - "Radiological, endoscopic, and pathological studies revealed a dramatic response to steroid injection from the fistula. "

03/08/2023 - "Prognostic model including the existence of complex fistula, disease activity at baseline and efficacy of IFX at 6 months may be useful to predict long-term outcome of luminal fistulizing CD patients."
01/01/2021 - "We aimed in this study to assess the rate of perianal and luminal relapse after surgically induced remission and to determine factors associated with fistula relapse. "
01/01/2017 - "Data from early-phase studies have suggested efficacy for luminal disease when allogeneic MSC were given intravenously and also suggested efficacy for fistulising disease when either allogeneic or autologous MSC were administered into fistulas. "
12/01/1999 - "Nine achieved clinical remission (3 luminal, 6 fistula patients). "
12/01/1999 - "Clinical remission was defined as a total CDAI < 150 (luminal patients) or >/=2+ for all parameters of the GIS (fistula patients). "

06/01/2019 - "The coronary-pulmonary artery fistula was running on the roof of the left atrium and was ligated with metal clips under thoracoscopic vision. "
07/01/2015 - "A permanent re-entry fistula was created in 13 sheep using a method in which a fold of rumen is exteriorised and held by a metal clamp. "
07/01/2014 - "The indications for surgery in spinal GSW are deterioration of the neurologic condition in a patient with incomplete neurological deficit, the presence of liquor fistula, spinal instability, intoxication by the metal from the bullet or risk of bullet migration. "
01/01/2007 - "For the closure of the GCF, the endoscopic metal clips were used to close the fistula."
08/01/2006 - "Aortoenteric fistula as a late complication of thrombolysis and bare metal stenting for perioperative occlusion of aortofemoral bypass."

02/01/2002 - "Recently, Somatostatin was shown to be highly effective in closure of refractory lymphatic fistulas. "
02/03/2023 - "The postoperative usage of somatostatin was not associated with recurrent fistula (13 in PSM Somatostatin group vs. 22 in PSM Non-somatostatin group; unadjusted OR 0.48; 95% CI 0.21-1.07; P = 0.07), while its postoperative usage decreased the incidence of recurrent high-output fistula (5/60 in the PSM Somatostatin group, compared with 13/60 in the PSM Non-somatostatin group; adjusted OR 0.30; 95% CI 0.09-0.95). "
02/15/1991 - "Previous reports and our own results indicate that this somatostatin analogue may be very useful in the nonsurgical treatment of GI tract fistulas."
12/01/2012 - "Several randomized control trials (RCTs) have compared somatostatin and its analogues versus a control group in patients with enterocutaneous fistulas (ECF). "
05/01/2012 - "We searched Medline, EMBase, the Cochrane Central Register of Controlled Trials, as well as reference lists of textbooks and relevant articles for randomized controlled trials (RCT) comparing somatostatin analogues to control in the treatment of postoperative enterocutaneous fistulas. "

01/01/2022 - "Higher anti-tumor necrosis factor-α (TNF) drug levels are associated with improved clinical healing of Crohn's perianal fistulas. "
01/01/2022 - "Higher Anti-tumor Necrosis Factor-α Levels Correlate With Improved Radiologic Outcomes in Crohn's Perianal Fistulas."
12/01/2016 - "This case report highlights the efficacy of anti-TNF alpha agents in the treatment of a bilioenteric fistula because it increases the probability of clinical remission and mucosal healing and therefore reduces the need for surgical treatment which may be associated morbidity."
11/02/2023 - "Pooled RRs for anti-tumor necrosis factor (TNF) agents were not statistically significant for induction (RR 1.36, 95% CI 0.97-1.91) or maintenance of fistula response (RR 1.48, 95% CI 0.97-2.27). "
01/01/2023 - "Most patients had one fistula (79%) and had prior anti-tumor necrosis factor-α treatment (98% in UST group, 80% in VDZ group, p = 0.01). "

01/01/1997 - "The method of "biological" filling based on the results of the study of fistulas' pathogenesis, usage of a rational therapy and capillary drain appeared to be the most effective in treatment of this complication. "
10/01/2018 - "Mesenchymal stem cell therapy is a promising treatment for perianal Crohn's fistulas refractory to conventional therapy, which are an extremely morbid complication and a true therapeutic challenge. "
01/01/2015 - "Combination therapy set on anti-TNF-α is until now the best option both to achieve fistula healing and avoid recurrence."
01/01/1995 - "In this study, we evaluated the efficacy of long-term seton drainage in the management of 13 patients with severe perianal Crohn's fistulas which had proven to be intractable to conventional therapy. "
12/01/2015 - "Overall, combination therapy was no more effective than monotherapy in inducing 6-month remission (odds ratio [OR], 1.02; 95% confidence interval [CI], 0.80-1.31), inducing a response (OR, 1.08; 95% CI, 0.79-1.48), maintaining a response (OR, 1.53; 95% CI, 0.67-3.49), or inducing partial (OR, 1.25; 95% CI, 0.84-1.88) or complete fistula closure (OR, 1.10; 95% CI, 0.68-1.78). "

05/01/2015 - "In cases in which there is a diffuse shunt in the affected sinus and no evident shunt point, such as in AVFs involving venous pouches and parasinuses, sealing the fistula orifice with self-expandable stents and angioplasty (balloon inflation) is considered the best treatment option to preserve normal cerebral venous sinus drainage and obliterate shunt flow. "
01/01/2019 - "The patient was treated successfully with fresh frozen plasma, the fistula was surgically repaired and a stent was placed. "
03/01/2015 - "[Utero-iliac fistula - successful therapy with stent graft implantation]."
01/01/2013 - "Statistical analysis showed a significant reduction in the rate of fistula development, from 45 to 9 per cent (p < 0.01), with application of the salivary stent. "
01/01/2023 - "CONCLUSIONS : TTTS was an effective and safe method for the closure of large gastrointestinal defects and could be used for fistula closure and stent fixation, making it a valuable addition to the armamentarium of endoscopic closure devices."

10/01/1975 - "Best results are achieved by ligature of the hepatic artery in cases of central, or by partial resection of the liver in cases of peripheral localization of the fistula."
11/01/2021 - "Although 30-70% of SIH patients show marked improvement following epidural blood patches applied via various techniques definite cure mostly requires surgical closure of ventral dural tears and surgical ligations of leaking nerve root sleeves associated with meningeal diverticulae or CSF-venous fistulas. "
08/01/2012 - "Gold-standard right heart catheterization findings have-for the first time-proven that following surgical shunt ligation of the A-V fistula, haemodynamics normalized completely in this patient. "
07/01/1992 - "Even though complete excision of the fistula represents the ideal treatment of this type of lesion, simple ligation can provide good results when the size of the fistula contraindicates embolization."
05/01/2016 - "Ligation of the intersphincteric fistula tract (LIFT) is a new sphincter-sparing surgical technique increasingly used to treat fistulae-in-ano yielding good results. "

04/01/2003 - "While native AV fistulae are considered the 'gold standard' for hemodialysis patients in need of long-term access, synthetic grafts are the best option for patients who are not candidates for an AV fistula. "
10/21/2023 - "Hemodialysis needs a vascular access to connect to the extracorporeal machine. In the last few years percutaneous endovascular arterio-venous fistula technique has been increasingly employed with very promising results. "
07/13/2021 - "Her abdominal fistula resolved completely, and she was maintained on hemodialysis for few years before she received a kidney transplant. "
03/01/2008 - "Vascular ultrasound has been proven to be effective in the assessment of hemodialysis fistulas providing noninvasive diagnostic work-up of vascular morphology and hemodynamics. "
12/01/2005 - "The PTD is effective for percutaneous treatment of thrombosed hemodialysis fistulas, with good short- and long-term outcomes in a U.S. "

05/25/2017 - "During following up of 3 to 12 (average 8.7) months, 1 case of anastomotic fistula occurred in each group and was cured by conservative treatment without significant difference [3.3%(1/30) vs. 3.1%(1/32), P=1.000]. "
12/01/2014 - "If conservative treatment failed with TEF, the surgical repair should be carried timely, By double sutured with fistula in surgery, and reinforced with the approaching muscle tissue, It can achieve good results."
03/01/2008 - "Use of cell technologies for closure of urethral fistulas demonstrates high efficacy of the method for conservative management of long urethral fistulas of a small diameter. "
01/01/2004 - "Conservative treatment has a good outcome for these fistulas. "
12/01/1997 - "[A case of esophagopleural fistula successfully cured by conservative therapy after middle and lower lobectomy of right lung]."