[A Case of Remission of Metastatic Germ Cell Tumor in an Elderly Patient by Multimodal Treatment].

Abstract

There have been few reports of multimodal treatment such as chemotherapy and surgical resection for testicular tumors over 40 years old. In this case, a 64-year-old man with nonseminoma, pT2N2M1aS1, stage IIIb, IGCCC good prognosis completed induction chemotherapy, followed by retroperitoneal lymph node dissection and resection of lung metastases. Chemotherapy (4 courses of etoposide and cisplatin therapy) was completed without serious adverse events other than grade 4 neutropenia. Resection of the residual tumor confirmed no viable tumor cells. There was no evidence of recurrence or elevation of tumor markers in the following 6 months. Similar cases could increase with the increase of testicular tumors in the elderly.

• Authors: Hiroki Osaki, Kazuaki Yamanaka, Toyofumi Abe, Shinichiro Fukuhara, Motohide Uemura, Hiroshi Kiuchi, Ryoichi Imamura, Norio Nonomura
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 68 Issue 12 Pg. 391-394 (Dec 2022) ISSN: 0018-1994 [Print] Japan
• PMID: 36627773 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Etoposide
• Cisplatin

Topics

• Male
• Humans
• Aged
• Middle Aged
• Adult
• Neoplasms, Germ Cell and Embryonal (drug therapy, surgery)
• Testicular Neoplasms (drug therapy, surgery)
• Combined Modality Therapy
• Etoposide (therapeutic use)
• Cisplatin
• Lymph Node Excision
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)