HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

An outbreak of work-related asthma and silicosis at a US countertop manufacturing and fabrication facility.

AbstractBACKGROUND:
Outbreaks of severe silicosis have affected workers who fabricate artificial stone countertops. Work-related asthma (WRA) has not been a prominent feature of those prior outbreaks.
METHODS:
This report describes an outbreak of WRA and silicosis at a facility that manufactures and fabricates chemical-resistant countertops comprised of sand, epoxy resin, and phthalic anhydride (PA), a known respiratory sensitizer. The multi-disciplinary investigation included clinical examinations of workers, an industrial hygiene survey with qualitative and quantitative exposure assessments, and a cross-sectional questionnaire.
RESULTS:
Engineering controls and personal protective equipment were inadequate. Some workers were exposed to PA or silica above permissible exposure limits established by the Occupational Safety and Health Administration (OSHA). Clinical and epidemiologic investigations identified 16 workers with confirmed or suspected WRA. Two years later, after OSHA began to enforce its new silica standards, 12 workers received medical surveillance for silicosis. Of these 12 workers, four (33.3%) were diagnosed with silicosis based on abnormal chest computed tomography examinations.
CONCLUSIONS:
Artificial stone countertop workers can develop asthma or silicosis. Risk of asthma may be highest in workers exposed to asthmagens such as PA and epoxy resins while manufacturing the artificial stone material.
AuthorsAaron W Tustin, Sylvia Kundu-Orwa, Jeffrey Lodwick, Dawn L Cannon, Ronda B McCarthy
JournalAmerican journal of industrial medicine (Am J Ind Med) Vol. 65 Issue 1 Pg. 12-19 (01 2022) ISSN: 1097-0274 [Electronic] United States
PMID34671999 (Publication Type: Journal Article)
Copyright© 2021 Wiley Periodicals LLC.
Chemical References
  • Silicon Dioxide
Topics
  • Asthma (epidemiology, etiology)
  • Cross-Sectional Studies
  • Disease Outbreaks
  • Humans
  • Occupational Exposure (analysis, statistics & numerical data)
  • Silicon Dioxide
  • Silicosis (epidemiology, etiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: