Abstract | OBJECTIVE: METHODS:
mRNA expression of cytokines and their receptors was assessed by quantitative PCR in psoriasis skin samples, in SpA and RA synovial tissue (ST) samples and in fibroblast-like synoviocytes (FLS). Cytokines were measured in synovial fluid (SF) and FLS supernatants by ELISA. FLS were stimulated with IL-17A or IL-17F cytokines supplemented with tumor necrosis factor (TNF), or with pooled SF from patients with SpA or RA. RESULTS: CONCLUSION:
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Authors | Sijia Chen, Iris C Blijdorp, Leonieke J J van Mens, Rowann Bowcutt, Talia E Latuhihin, Marleen G H van de Sande, Stevan Shaw, Nataliya G Yeremenko, Dominique L P Baeten |
Journal | The Journal of rheumatology
(J Rheumatol)
Vol. 47
Issue 11
Pg. 1606-1613
(11 01 2020)
ISSN: 0315-162X [Print] Canada |
PMID | 31941804
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Arthritis, Rheumatoid
(immunology)
- Cells, Cultured
- Humans
- Interleukin-17
- Spondylarthritis
(immunology)
- Synovial Membrane
- Synoviocytes
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