Comparison of Curative Effects between Minimally Invasive Percutaneous Lag Screw Internal Fixation and Reconstruction Plate for Unstable Pelvic Fractures.

Abstract

OBJECTIVE:

To compare the clinical efficacy of minimally invasive percutaneous lag screw internal fixation and reconstruction plate in the treatment of unstable pelvic fractures.

STUDY DESIGN:

An experimental study.

PLACE AND DURATION OF STUDY:

The Department of Orthopaedics, Second People's Hospital of Liaocheng, Linqing City, China, from January 2016 to March 2018.

METHODOLOGY:

A total of 130 patients with unstable pelvic fracture were randomly divided into group A and group B, with 65 cases in each group. Group A was treated with minimally invasive percutaneous lag screw internal fixation, and group B was treated with reconstruction plate. Clinical efficacy of two groups after treatment was evaluated. Serum alkaline phosphatase (ALP), tumor necrosis factor-α (TNF-α), C-reactive protein (CRP), stress hormones cortisol (Cor), angiotensin II (Ang II), and norepinephrine (NE) contents were compared.

RESULTS:

After treatment, the excellent and good rate in group A was higher than that in group B (p=0.005). At 7 days after the operation, serum ALP level in group A was higher than that in group B (p <0.001), serum TNF-α, CRP, Cor, Ang II, and NE levels were lower in group A than those in group B (all p <0.001).

CONCLUSION:

Compared with reconstruction plate, minimally invasive percutaneous lag screw internal fixation has better clinical efficacy in patients with unstable pelvic fractures; meanwhile, it can effectively increase serum ALP level, reduce the levels of inflammatory cytokines TNF-α and CRP, and effectively reduce surgical trauma as well as postoperative body stress response.

• Authors: Jifeng Fang, Hui Dong, Zihui Li
• Journal: Journal of the College of Physicians and Surgeons--Pakistan : JCPSP (J Coll Physicians Surg Pak) Vol. 30 Issue 1 Pg. 28-32 (Jan 2020) ISSN: 1681-7168 [Electronic] Pakistan
• PMID: 31931928 (Publication Type: Journal Article, Randomized Controlled Trial)

Topics

• Bone Plates
• Bone Screws
• Female
• Fracture Fixation, Internal (instrumentation, methods)
• Fracture Healing
• Fractures, Bone (diagnosis, etiology, surgery)
• Humans
• Male
• Minimally Invasive Surgical Procedures
• Pelvic Bones (injuries)
• Treatment Outcome