Abstract | AIM: MATERIALS AND METHODS: CYP1B1 expression was detected in human periodontitis samples, mice with ligature-induced periodontitis and lipopolysaccharide (LPS)-induced inflammation in periodontal ligament cells (PDLCs) in vitro. FICZ was administered topically or systemically. The therapeutic functions of FICZ were detected via qPCR, micro-computed tomography and immunohistochemistry. Finally, the mechanisms of AhR signalling in periodontitis were investigated by cell assays. RESULTS: CONCLUSION:
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Authors | Jing Huang, Xinjie Cai, Yanjing Ou, Le Fan, Yi Zhou, Yining Wang |
Journal | Journal of clinical periodontology
(J Clin Periodontol)
Vol. 46
Issue 9
Pg. 882-893
(09 2019)
ISSN: 1600-051X [Electronic] United States |
PMID | 31286538
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Receptors, Aryl Hydrocarbon
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Topics |
- Alveolar Bone Loss
- Animals
- Humans
- Inflammation
- Mice
- Periodontitis
- Receptors, Aryl Hydrocarbon
- X-Ray Microtomography
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