Abstract | BACKGROUND: PURPOSE: METHODS: Systematic review of Cochrane Register of Controlled Trials, PubMed, and EMBASE databases was conducted (January 1987-December 2016), in accordance with PRISMA. RESULTS: Twelve retrospective studies were identified (568 patients total); 31, 334, and 203 patients underwent one-, two-, and three-stage procedures, respectively. Median study size was 31 patients (range 10-202), median age was 13 years (range 2-21), median follow-up was 4 years (range 0.08-16). Postoperative complications included pouchitis, bowel obstruction, stricture, fistula, pouch failure, anastomotic leak, and wound infections. Calcineurin inhibitor usage improved pediatric ulcerative colitis activity index (PUCAI) score. Higher PUCAI scores correlated with likelihood of staged procedures. Number of stages did not restrict quality of life. CONCLUSIONS: Paucity of data exists, comparing preoperative factors leading to staged procedures in pediatric UC. This systematic review identifies an area for future studies. LEVEL OF EVIDENCE: II.
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Authors | Sharman P Tan Tanny, Minjung Yoo, John M Hutson, Jacob C Langer, Sebastian K King |
Journal | Journal of pediatric surgery
(J Pediatr Surg)
Vol. 54
Issue 7
Pg. 1324-1330
(Jul 2019)
ISSN: 1531-5037 [Electronic] United States |
PMID | 30241963
(Publication Type: Journal Article, Systematic Review)
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Copyright | Crown Copyright © 2018. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adolescent
- Child
- Child, Preschool
- Colitis, Ulcerative
(physiopathology, surgery)
- Female
- Humans
- Male
- Predictive Value of Tests
- Proctocolectomy, Restorative
(methods)
- Quality of Life
- Retrospective Studies
- Young Adult
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