Abstract | RATIONALE: PATIENT CONCERNS AND DIAGNOSES: A 2-year-old female with AML with MLL rearrangement presented with CNS infiltration. Laboratory tests suggested the presence of central hypothyroidism ( thyroid-stimulating hormone [TSH]: 0.48 mIU/ml, normal range 0.7-6.4 mIU/ml; serum free thyroxine [FT4]: 0.62 ng/dl, normal range 0.8-2.2 ng/dl; free triiodothyronine: 1.57 pg/ml, normal range 2.7-5.6 pg/ml). Magnetic resonance imaging detected no lesions in the hypothalamus, pituitary, or thyroid. INTERVENTIONS AND OUTCOMES: LESSONS:
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Authors | Yuya Sato, Satomi Koyama, Shigeko Kuwashima, Masaya Kato, Mayuko Okuya, Keitaro Fukushima, Hidemitsu Kurosawa, Osamu Arisaka |
Journal | Medicine
(Medicine (Baltimore))
Vol. 96
Issue 26
Pg. e7329
(Jun 2017)
ISSN: 1536-5964 [Electronic] United States |
PMID | 28658145
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Central Nervous System Neoplasms
(complications, diagnostic imaging, drug therapy, metabolism)
- Child, Preschool
- Diagnosis, Differential
- Female
- Humans
- Hypothyroidism
(complications, diagnostic imaging, drug therapy)
- Leukemia, Monocytic, Acute
(complications, diagnostic imaging, drug therapy, pathology)
- Thyrotropin
(blood)
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