[The effects of preparation "Histochrome" in biochemical parameters of blood for patients with cardiopathologies].

Abstract

The effects of the small doses of the preparation Gistochrome, containing natural polyhydroxynaphtoquinoine echinochrom A from flat sea urchin Scaphechinus mirabilis, on blood biochemical parameters have been studied in patients with cardiovascular diseases. Gistochrome administration influenced the LPO-antioxidant protection system, indicating reinforcement of antioxidant protection mechanisms. Gistochrome modulated the immune status and the plasma cytokine profile. Thus, Gistochrome may be recommended as means of additional therapy for patients with cardiovascular diseases for correcting the metabolic, immunological and redox impairments.

• Authors: A V Tsybulskiĭ, A M Popov, A A Artiukhov, O N Krivoshapko, É P Kozlovskaia, L N Bogdanovich, S P Kryzhanovskiĭ, Iu G Blinov
• Journal: Biomeditsinskaia khimiia (Biomed Khim) 2014 Jan-Feb Vol. 60 Issue 1 Pg. 115-24 ISSN: 2310-6972 [Print] Russia (Federation)
• PMID: 24749252 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antigens, CD
• Antioxidants
• Cholesterol, HDL
• Cholesterol, LDL
• Cholesterol, VLDL
• Cytokines
• Immunologic Factors
• Naphthoquinones
• Triglycerides
• Malondialdehyde
• echinochrome A

Topics

• Animals
• Antigens, CD (metabolism)
• Antioxidants (isolation & purification, therapeutic use)
• Atherosclerosis (blood, drug therapy, physiopathology)
• Blood Cell Count
• Case-Control Studies
• Cholesterol, HDL (blood)
• Cholesterol, LDL (blood)
• Cholesterol, VLDL (blood)
• Cytokines (metabolism)
• Humans
• Hypertension (blood, drug therapy, physiopathology)
• Immunologic Factors (isolation & purification, therapeutic use)
• Injections, Intramuscular
• Lipid Peroxidation (drug effects)
• Malondialdehyde (blood)
• Middle Aged
• Myocardial Ischemia (blood, drug therapy, physiopathology)
• Naphthoquinones (isolation & purification, therapeutic use)
• Oxidation-Reduction (drug effects)
• Sea Urchins (chemistry)
• Triglycerides (blood)