Abstract | BACKGROUND: METHODS: Effect of chronic arsenic exposure on liver was determined by liver function tests. Autoimmune status was measured by measuring ANA and anti-dsDNA in serum. Inflammatory cytokines associated with increased cardiovascular disease risk, IL6, IL8 and MCP-1 were determined. RESULTS: CONCLUSIONS: Chronic arsenic exposure causes liver injury, increases the serum levels of autoimmune markers and imparts increased cardiovascular risk.
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Authors | Nandana Das, Somnath Paul, Debmita Chatterjee, Nilanjana Banerjee, Niladri S Majumder, Nilendu Sarma, Tanmoy J Sau, Santanu Basu, Saptarshi Banerjee, Papiya Majumder, Apurba K Bandyopadhyay, J Christopher States, Ashok K Giri |
Journal | BMC public health
(BMC Public Health)
Vol. 12
Pg. 639
(Aug 10 2012)
ISSN: 1471-2458 [Electronic] England |
PMID | 22883023
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antibodies, Antinuclear
- Biomarkers
- Chemokine CCL2
- Drinking Water
- Interleukin-6
- Interleukin-8
- Water Pollutants, Chemical
- Arsenic
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Topics |
- Adolescent
- Adult
- Aged
- Antibodies, Antinuclear
(blood)
- Arsenic
(analysis)
- Arsenic Poisoning
(physiopathology)
- Biomarkers
(blood)
- Cardiovascular Diseases
(blood, chemically induced)
- Chemokine CCL2
(blood)
- Drinking Water
(chemistry)
- Female
- Humans
- India
- Interleukin-6
(blood)
- Interleukin-8
(blood)
- Liver
(immunology, injuries, physiopathology)
- Liver Diseases
(blood, etiology)
- Male
- Middle Aged
- Risk Assessment
(methods)
- Water Pollutants, Chemical
(poisoning)
- Young Adult
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