Abstract | BACKGROUND: OBJECTIVE: We investigated the immunohistochemical expression of MGMT in a variety of corticotroph adenoma subtypes to determine the potential utility of temozolomide as a therapeutic agent. METHODS: RESULTS: CONCLUSION:
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Authors | Fateme Salehi, Bernd W Scheithauer, Kalman Kovacs, Eva Horvath, Luis V Syro, Soniya Sharma, Branavan Manoranjan, Michael Cusimano |
Journal | Neurosurgery
(Neurosurgery)
Vol. 70
Issue 2
Pg. 491-6; discussion 496
(Feb 2012)
ISSN: 1524-4040 [Electronic] United States |
PMID | 21822153
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers, Tumor
- Tumor Suppressor Proteins
- DNA Modification Methylases
- MGMT protein, human
- DNA Repair Enzymes
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Topics |
- ACTH-Secreting Pituitary Adenoma
(metabolism)
- Adenoma
(metabolism)
- Adult
- Biomarkers, Tumor
(analysis)
- DNA Modification Methylases
(analysis, biosynthesis)
- DNA Repair Enzymes
(analysis, biosynthesis)
- Female
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Tumor Suppressor Proteins
(analysis, biosynthesis)
- Young Adult
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