Abstract | BACKGROUND: Chikungunya virus (CHIKV) infection induces arthralgia. The involvement of inflammatory cytokines and chemokines has been suggested, but very little is known about their secretion profile in CHIKV-infected patients. METHODS: A case-control longitudinal study was performed that involved 30 adult patients with laboratory-confirmed Chikungunya fever. Their profiles of clinical disease, viral load, and immune mediators were investigated. RESULTS: CONCLUSIONS:
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Authors | Angela Chow, Zhisheng Her, Edward K S Ong, Jin-miao Chen, Frederico Dimatatac, Dyan J C Kwek, Timothy Barkham, Henry Yang, Laurent Rénia, Yee-Sin Leo, Lisa F P Ng |
Journal | The Journal of infectious diseases
(J Infect Dis)
Vol. 203
Issue 2
Pg. 149-57
(Jan 15 2011)
ISSN: 1537-6613 [Electronic] United States |
PMID | 21288813
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adult
- Aged
- Alphavirus Infections
(immunology, pathology)
- Arthralgia
(etiology)
- Arthritis
(immunology, pathology, virology)
- Blood
(immunology, virology)
- Case-Control Studies
- Chikungunya Fever
- Chikungunya virus
(immunology, pathogenicity)
- Cytokines
(blood)
- Female
- Humans
- Longitudinal Studies
- Male
- Middle Aged
- Viral Load
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