HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Use of a retrievable metallic stent internally coated with silicone to treat airway obstruction.

AbstractPURPOSE:
The authors hypothesized that internally covered stents can reduce the rates of stent migration or mucous retention. The authors performed this study to report their experience with use of a retrievable metallic stent internally coated with silicone in patients with benign or malignant central airway obstructions.
MATERIALS AND METHODS:
From 2004 to 2007, the authors performed fluoroscopically guided placement of a retrievable metallic stent internally coated with silicone in 26 consecutive patients with benign (n = 5) and malignant (n = 21) central airway obstructions. Stents were woven from a single thread of a 0.2-mm-diameter nitinol wire in a tubular configuration and internally covered with silicone membrane.
RESULTS:
Stent placement was technically and clinically successful in 93% (25/26) and 85% (22/26) of the patients, respectively. There were eight complications (31%) after stent placement, including tumor overgrowth (n = 2), stent migration (n = 1), symptomatic granulation tissue formation (n = 1), severe pain (n = 1), improper stent location (n = 1), symptomatic sputum retention (n = 1) and esophagobronchial fistula (n = 1). Because of complications, five stents were removed with a retrieval hook under fluoroscopic guidance without difficulty. The median survival period and stent patency were 150.0 days +/- 91.4 and 143.0 days +/- 26.7, respectively.
CONCLUSIONS:
The use of a retrievable metallic stent internally coated with silicone is a safe and effective method for relieving dyspnea, with adequate stent patency in patients with benign or malignant central airway obstructions. This stent design seems to be less prone to migration or mucous retention.
AuthorsJin Hyoung Kim, Ji Hoon Shin, Ho-Young Song, Se Chul Lee, Kyung Rae Kim, Jung-Hoon Park
JournalJournal of vascular and interventional radiology : JVIR (J Vasc Interv Radiol) Vol. 19 Issue 8 Pg. 1208-14 (Aug 2008) ISSN: 1535-7732 [Electronic] United States
PMID18656015 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Coated Materials, Biocompatible
  • Metals
  • Silicones
Topics
  • Aged
  • Airway Obstruction (diagnostic imaging, surgery)
  • Coated Materials, Biocompatible (chemistry)
  • Device Removal (methods)
  • Equipment Failure Analysis
  • Female
  • Humans
  • Male
  • Metals
  • Middle Aged
  • Radiography, Interventional
  • Silicones (chemistry)
  • Stents

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: